Potential application of proteolysis targeting chimera (PROTAC) modification technology in natural products for their targeted protein degradation
There are numerous evaluations of natural products, of which majority are food bioactives, performed up to date for their various health beneficial activities via targeting specific proteins. However, the direct identification of a targeted protein remains unexplored for natural occurring compounds....
Saved in:
Main Authors: | Guliang Yang, Haiyan Zhong, Xinxin Xia, Zhiwen Qi, Chengzhang Wang, Shiming Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Tsinghua University Press
2022-03-01
|
Series: | Food Science and Human Wellness |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453021000951 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
PROTAC-based therapeutics for targeting HPV oncoproteins in head and neck cancers
by: Nobendu Mukerjee, et al.
Published: (2025-12-01) -
PROTACs: Mechanism and Bioavailability enhancement strategies by nanotechnology, RNA viral infections (vaccine strategy) and Prodrug development
by: Sanaul Mustafa, et al.
Published: (2025-01-01) -
A pH-responsive PROTAC-based nanosystem triggers tumor-specific ferroptosis to construct in situ tumor vaccines
by: Linghong Huang, et al.
Published: (2025-04-01) -
Influenza A virus hemagglutinin: from classical fusion inhibitors to proteolysis targeting chimera-based strategies in antiviral drug discovery
by: Francisco Javier Hermoso-Pinilla, et al.
Published: (2024-02-01) -
Non-enzymatic protein targeting agents as a promising strategy for cancer treatment
by: Madison Ambrose, et al.
Published: (2025-01-01)