Prognostic Value of Cerebrospinal Fluid and Serum Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: A Correlation Study

Prognostic Value of Cerebrospinal Fluid and Serum Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: A Correlation Study

ABSTRACT Background The diagnostic and prognostic values of serum neurofilament light chain (sNfL), in comparison to cerebrospinal fluid (CSF) neurofilament light chain (cNfL), and other clinical parameters in amyotrophic lateral sclerosis (ALS) at the time of diagnosis remain elusive. Methods We ex...

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Bibliographic Details
Main Authors:	Siqi Dong, Xiaoni Liu, Yanni Zhou, Jiatong Li, Zihan Qi, Zihan Wang, Wenbo Yang, Xiangjun Chen
Format:	Article
Language:	English
Published:	Wiley 2025-01-01
Series:	Brain and Behavior
Subjects:	amyotrophic lateral sclerosis biomarker diagnosis neurofilament light chain prognosis
Online Access:	https://doi.org/10.1002/brb3.70256
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