Mismatch Repair Status and Lymph Node Ratio in Survival Prediction of Stage II/III Rectal Cancer Patients: A Comprehensive Analysis of a Multi‐Center Retrospective Study

Mismatch Repair Status and Lymph Node Ratio in Survival Prediction of Stage II/III Rectal Cancer Patients: A Comprehensive Analysis of a Multi‐Center Retrospective Study

ABSTRACT Background The microsatellite status (dMMR vs. pMMR) in colorectal cancer can serve as a guiding factor for patient prognosis and treatment, where dMMR status indicates a better prognosis and often obviates the need for adjuvant chemotherapy (ACT). Conversely, a higher lymph node ratio (LNR...

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Bibliographic Details
Main Authors: Kailong Zhao, Wenwen Pang, Xinyu Liu, Kemin Ni, Weifeng Gao, Zhiquan Tan, Jun Xue, Weizheng Liang, Xueliang Wu, Xipeng Zhang, Xiaomin Su, Chunze Zhang
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Cancer Medicine
Subjects:
adjuvant chemotherapy (ACT)
lymph node ratio (LNR)
microsatellite instability (dMMR)
survival
Online Access:https://doi.org/10.1002/cam4.70756
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