Context-specific eQTLs provide deeper insight into causal genes underlying shared genetic architecture of COVID-19 and idiopathic pulmonary fibrosis

Context-specific eQTLs provide deeper insight into causal genes underlying shared genetic architecture of COVID-19 and idiopathic pulmonary fibrosis

Summary: Most genetic variants identified through genome-wide association studies (GWASs) are suspected to be regulatory in nature, but only a small fraction colocalize with expression quantitative trait loci (eQTLs, variants associated with expression of a gene). Therefore, it is hypothesized but l...

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Bibliographic Details
Main Authors: Trisha Dalapati, Liuyang Wang, Angela G. Jones, Jonathan Cardwell, Iain R. Konigsberg, Yohan Bossé, Don D. Sin, Wim Timens, Ke Hao, Ivana Yang, Dennis C. Ko
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:HGG Advances
Subjects:
GWAS
eQTL
IPF
COVID-19
ATP11A
DPP9
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247725000132
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