Meningitis In Newborns With Late-Onset Sepsis; A Critical Insight

Objective: To determine the frequency of meningitis in neonates with late-onset sepsis Methods: A cross-sectional study was conducted at Hameed Latif Teaching Hospital, Lahore from March 2023 to August 2023. 210 neonates were enrolled through non-probability consecutive sampling. After obtaining...

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Main Authors: Sobia Naveed, Madiha Fayyaz, Somayya Siddiqa, Asvar Samaa, Rahat Rahman, Zartasha Sial
Format: Article
Language:English
Published: Rawalpindi Medical University 2024-09-01
Series:Journal of Rawalpindi Medical College
Online Access:https://www.journalrmc.com/index.php/JRMC/article/view/2377
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author Sobia Naveed
Madiha Fayyaz
Somayya Siddiqa
Asvar Samaa
Rahat Rahman
Zartasha Sial
author_facet Sobia Naveed
Madiha Fayyaz
Somayya Siddiqa
Asvar Samaa
Rahat Rahman
Zartasha Sial
author_sort Sobia Naveed
collection DOAJ
description Objective: To determine the frequency of meningitis in neonates with late-onset sepsis Methods: A cross-sectional study was conducted at Hameed Latif Teaching Hospital, Lahore from March 2023 to August 2023. 210 neonates were enrolled through non-probability consecutive sampling. After obtaining written informed consent from parents, all septic neonates who fulfilled the inclusion criteria were enrolled in the study. In each neonate with clinical features of sepsis, a detailed history and examination were done. Meningitis was labelled in the neonates whose CSF findings were suggestive of meningitis. Cranial ultrasound was done in all neonates with meningitis to rule out any complication.Data was entered and analyzed using SPSS version 23.Data was stratified for age,weight,gestational age and gender to deal with effect modifiers.For post stratification,Chi-square test was applied to see the significance.A p-value ≤0.05 was considered as significant. Results: A total of 210 children presenting with late-onset sepsis were included. Among these children 122(58.1%) were males, while 88(41.9%) were females. The age range in this study was from 7 to 28 days with mean age of 17.7±6.3 days. It was found that out of 210 neonates with late-onset sepsis,47(22.4%) had meningitis. Conclusion: The frequency of meningitis in patients with late-onset neonatal sepsis is quite high. Meningitis is a deadly disease which is associated with lifelong morbidity and sometimes mortality. Therefore screening for neonatal meningitis should be done in all patients afflicted by neonatal sepsis.
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1683-3570
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spelling doaj-art-4e0eb69ecc7246c0ad675a166b9488992025-02-06T08:35:58ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702024-09-0128310.37939/jrmc.v28i3.2377Meningitis In Newborns With Late-Onset Sepsis; A Critical Insight Sobia NaveedMadiha Fayyaz0Somayya SiddiqaAsvar SamaaRahat RahmanZartasha SialHameed Latif Teaching Hospital Lahore Objective: To determine the frequency of meningitis in neonates with late-onset sepsis Methods: A cross-sectional study was conducted at Hameed Latif Teaching Hospital, Lahore from March 2023 to August 2023. 210 neonates were enrolled through non-probability consecutive sampling. After obtaining written informed consent from parents, all septic neonates who fulfilled the inclusion criteria were enrolled in the study. In each neonate with clinical features of sepsis, a detailed history and examination were done. Meningitis was labelled in the neonates whose CSF findings were suggestive of meningitis. Cranial ultrasound was done in all neonates with meningitis to rule out any complication.Data was entered and analyzed using SPSS version 23.Data was stratified for age,weight,gestational age and gender to deal with effect modifiers.For post stratification,Chi-square test was applied to see the significance.A p-value ≤0.05 was considered as significant. Results: A total of 210 children presenting with late-onset sepsis were included. Among these children 122(58.1%) were males, while 88(41.9%) were females. The age range in this study was from 7 to 28 days with mean age of 17.7±6.3 days. It was found that out of 210 neonates with late-onset sepsis,47(22.4%) had meningitis. Conclusion: The frequency of meningitis in patients with late-onset neonatal sepsis is quite high. Meningitis is a deadly disease which is associated with lifelong morbidity and sometimes mortality. Therefore screening for neonatal meningitis should be done in all patients afflicted by neonatal sepsis. https://www.journalrmc.com/index.php/JRMC/article/view/2377
spellingShingle Sobia Naveed
Madiha Fayyaz
Somayya Siddiqa
Asvar Samaa
Rahat Rahman
Zartasha Sial
Meningitis In Newborns With Late-Onset Sepsis; A Critical Insight
Journal of Rawalpindi Medical College
title Meningitis In Newborns With Late-Onset Sepsis; A Critical Insight
title_full Meningitis In Newborns With Late-Onset Sepsis; A Critical Insight
title_fullStr Meningitis In Newborns With Late-Onset Sepsis; A Critical Insight
title_full_unstemmed Meningitis In Newborns With Late-Onset Sepsis; A Critical Insight
title_short Meningitis In Newborns With Late-Onset Sepsis; A Critical Insight
title_sort meningitis in newborns with late onset sepsis a critical insight
url https://www.journalrmc.com/index.php/JRMC/article/view/2377
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AT somayyasiddiqa meningitisinnewbornswithlateonsetsepsisacriticalinsight
AT asvarsamaa meningitisinnewbornswithlateonsetsepsisacriticalinsight
AT rahatrahman meningitisinnewbornswithlateonsetsepsisacriticalinsight
AT zartashasial meningitisinnewbornswithlateonsetsepsisacriticalinsight