Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy
A 47-year-old Japanese man was diagnosed with prostate cancer in February 1995 (Initial PSA 77.2 ng/mL, GS3 + 4, cT3N0M0). He underwent radical prostatectomy after androgen deprivation therapy (ADT) in June 1995. Nine years after operation, he was diagnosed with local recurrence of prostate cancer a...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2015/839738 |
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| author | Shogo Hosogoe Osamu Soma Teppei Matsumoto Atsushi Imai Shingo Hatakeyama Takahiro Yoneyama Yasuhiro Hashimoto Takuya Koie Chikara Ohyama Masahiko Aoki |
| author_facet | Shogo Hosogoe Osamu Soma Teppei Matsumoto Atsushi Imai Shingo Hatakeyama Takahiro Yoneyama Yasuhiro Hashimoto Takuya Koie Chikara Ohyama Masahiko Aoki |
| author_sort | Shogo Hosogoe |
| collection | DOAJ |
| description | A 47-year-old Japanese man was diagnosed with prostate cancer in February 1995 (Initial PSA 77.2 ng/mL, GS3 + 4, cT3N0M0). He underwent radical prostatectomy after androgen deprivation therapy (ADT) in June 1995. Nine years after operation, he was diagnosed with local recurrence of prostate cancer and he received postoperative external beam radiation therapy (EBRT) (70 Gy). By May 2008, the PSA dropped to 0.33 ng/mL, and a CT scan showed that the mass had disappeared. On April 2012, the PSA once again rose to 3.1 ng/mL. CT scan and MRI revealed a mass in the prostatic bed. We diagnosed local recurrence of prostate cancer. We underwent salvage low-dose brachytherapy after obtaining informed consent. The prescribed dose of the salvage brachytherapy was 145 Gy to control the tumor considering the hormone resistant prostatic cancer and high-risk feature. PSA level rapidly decreased to 0.66 ng/mL by 6 months after seed implantation. No adverse events were seen during the follow-up period. |
| format | Article |
| id | doaj-art-4e0c82c796e1471198bbd0c52d1a8459 |
| institution | Kabale University |
| issn | 2090-696X 2090-6978 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-4e0c82c796e1471198bbd0c52d1a84592025-02-03T05:44:29ZengWileyCase Reports in Urology2090-696X2090-69782015-01-01201510.1155/2015/839738839738Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical ProstatectomyShogo Hosogoe0Osamu Soma1Teppei Matsumoto2Atsushi Imai3Shingo Hatakeyama4Takahiro Yoneyama5Yasuhiro Hashimoto6Takuya Koie7Chikara Ohyama8Masahiko Aoki9Department of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki 036-8562, JapanDepartment of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki 036-8562, JapanDepartment of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki 036-8562, JapanDepartment of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki 036-8562, JapanDepartment of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki 036-8562, JapanDepartment of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki 036-8562, JapanDepartment of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki 036-8562, JapanDepartment of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki 036-8562, JapanDepartment of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki 036-8562, JapanDepartment of Radiology, Hirosaki University Graduate School of Medicine, 5 Zaifucho, Hirosaki 036-8562, JapanA 47-year-old Japanese man was diagnosed with prostate cancer in February 1995 (Initial PSA 77.2 ng/mL, GS3 + 4, cT3N0M0). He underwent radical prostatectomy after androgen deprivation therapy (ADT) in June 1995. Nine years after operation, he was diagnosed with local recurrence of prostate cancer and he received postoperative external beam radiation therapy (EBRT) (70 Gy). By May 2008, the PSA dropped to 0.33 ng/mL, and a CT scan showed that the mass had disappeared. On April 2012, the PSA once again rose to 3.1 ng/mL. CT scan and MRI revealed a mass in the prostatic bed. We diagnosed local recurrence of prostate cancer. We underwent salvage low-dose brachytherapy after obtaining informed consent. The prescribed dose of the salvage brachytherapy was 145 Gy to control the tumor considering the hormone resistant prostatic cancer and high-risk feature. PSA level rapidly decreased to 0.66 ng/mL by 6 months after seed implantation. No adverse events were seen during the follow-up period.http://dx.doi.org/10.1155/2015/839738 |
| spellingShingle | Shogo Hosogoe Osamu Soma Teppei Matsumoto Atsushi Imai Shingo Hatakeyama Takahiro Yoneyama Yasuhiro Hashimoto Takuya Koie Chikara Ohyama Masahiko Aoki Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy Case Reports in Urology |
| title | Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy |
| title_full | Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy |
| title_fullStr | Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy |
| title_full_unstemmed | Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy |
| title_short | Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy |
| title_sort | salvage brachytherapy for castration resistant and external beam radiotherapy resistant local recurrence 17 years after radical prostatectomy |
| url | http://dx.doi.org/10.1155/2015/839738 |
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