Change in the Prevalence of Testing for Latent Tuberculosis Infection in the United States: 1999–2012
Purpose. There is no information on the change in prevalence of latent tuberculosis infection (LTBI) testing in the United States (US) following the introduction of the interferon gamma release assay (IGRA), a new and alternative diagnostic method for LTBI. The purpose of this study was to evaluate...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2016/1850879 |
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| author | Nicholas T. Vozoris Jane Batt |
| author_facet | Nicholas T. Vozoris Jane Batt |
| author_sort | Nicholas T. Vozoris |
| collection | DOAJ |
| description | Purpose. There is no information on the change in prevalence of latent tuberculosis infection (LTBI) testing in the United States (US) following the introduction of the interferon gamma release assay (IGRA), a new and alternative diagnostic method for LTBI. The purpose of this study was to evaluate potential changes in the prevalence of LTBI testing in the US following the introduction of IGRA. Methods. This was a multiyear cross-sectional study using nationally representative data from the 1999-2000 and 2011-2012 US National Health and Nutrition Examination Surveys. Self-reported prevalence of LTBI testing was estimated among groups known to have increased LTBI risk. Descriptive statistics were used. Results. Compared to 1999-2000, significantly fewer individuals self-reported being tested for LTBI in 2011-2012 among Hispanic Americans (68.0% versus 60.7%, p<0.0001) and among those with comorbidities (74.7% versus 72.0%, p=0.02). There were also nonsignificant trends towards less self-reported LTBI testing in 2011-2012 versus 1999-2000 among household contacts of active TB cases, foreign-born individuals, and African Americans. Conclusions. Despite the introduction of IGRA, LTBI testing occurs less frequently in the US among vulnerable groups. Possibly inadequate targeted LTBI testing could result in increased active TB in the US in the future. |
| format | Article |
| id | doaj-art-4e00e57afcb44b2e976d38dccbe0a8fc |
| institution | Kabale University |
| issn | 1198-2241 1916-7245 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-4e00e57afcb44b2e976d38dccbe0a8fc2025-02-03T01:20:48ZengWileyCanadian Respiratory Journal1198-22411916-72452016-01-01201610.1155/2016/18508791850879Change in the Prevalence of Testing for Latent Tuberculosis Infection in the United States: 1999–2012Nicholas T. Vozoris0Jane Batt1Tuberculosis Program, Division of Respirology, Department of Medicine, St. Michael’s Hospital, Toronto, ON, M5B 1W8, CanadaTuberculosis Program, Division of Respirology, Department of Medicine, St. Michael’s Hospital, Toronto, ON, M5B 1W8, CanadaPurpose. There is no information on the change in prevalence of latent tuberculosis infection (LTBI) testing in the United States (US) following the introduction of the interferon gamma release assay (IGRA), a new and alternative diagnostic method for LTBI. The purpose of this study was to evaluate potential changes in the prevalence of LTBI testing in the US following the introduction of IGRA. Methods. This was a multiyear cross-sectional study using nationally representative data from the 1999-2000 and 2011-2012 US National Health and Nutrition Examination Surveys. Self-reported prevalence of LTBI testing was estimated among groups known to have increased LTBI risk. Descriptive statistics were used. Results. Compared to 1999-2000, significantly fewer individuals self-reported being tested for LTBI in 2011-2012 among Hispanic Americans (68.0% versus 60.7%, p<0.0001) and among those with comorbidities (74.7% versus 72.0%, p=0.02). There were also nonsignificant trends towards less self-reported LTBI testing in 2011-2012 versus 1999-2000 among household contacts of active TB cases, foreign-born individuals, and African Americans. Conclusions. Despite the introduction of IGRA, LTBI testing occurs less frequently in the US among vulnerable groups. Possibly inadequate targeted LTBI testing could result in increased active TB in the US in the future.http://dx.doi.org/10.1155/2016/1850879 |
| spellingShingle | Nicholas T. Vozoris Jane Batt Change in the Prevalence of Testing for Latent Tuberculosis Infection in the United States: 1999–2012 Canadian Respiratory Journal |
| title | Change in the Prevalence of Testing for Latent Tuberculosis Infection in the United States: 1999–2012 |
| title_full | Change in the Prevalence of Testing for Latent Tuberculosis Infection in the United States: 1999–2012 |
| title_fullStr | Change in the Prevalence of Testing for Latent Tuberculosis Infection in the United States: 1999–2012 |
| title_full_unstemmed | Change in the Prevalence of Testing for Latent Tuberculosis Infection in the United States: 1999–2012 |
| title_short | Change in the Prevalence of Testing for Latent Tuberculosis Infection in the United States: 1999–2012 |
| title_sort | change in the prevalence of testing for latent tuberculosis infection in the united states 1999 2012 |
| url | http://dx.doi.org/10.1155/2016/1850879 |
| work_keys_str_mv | AT nicholastvozoris changeintheprevalenceoftestingforlatenttuberculosisinfectionintheunitedstates19992012 AT janebatt changeintheprevalenceoftestingforlatenttuberculosisinfectionintheunitedstates19992012 |