Integrative genomic analysis identifies DPP4 inhibition as a modulator of FGF17 and PDGFRA downregulation and PI3K/Akt pathway suppression leading to apoptosis

Integrative genomic analysis identifies DPP4 inhibition as a modulator of FGF17 and PDGFRA downregulation and PI3K/Akt pathway suppression leading to apoptosis

IntroductionProstate cancer (PCa) remains a significant global health challenge despite advancements in treatment strategies. There is a need to explore the molecular heterogeneity of PCa to facilitate the development of personalized treatment approaches. This study investigates the molecular hetero...

Full description

Saved in:
Bibliographic Details
Main Authors: Kiran Kumar Chitluri, Emerson Isaac Arnold
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
Linagliptin
prostate cancer
apoptosis
mutation
DPP4/CD26
PI3K/Akt pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1606914/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2025.1606914/full

Similar Items