Preclinical Studies of Chemotherapy Using Histone Deacetylase Inhibitors in Endometrial Cancer

Because epigenetic alterations are believed to be involved in the repression of tumor suppressor genes and promotion of tumorigenesis in endometrial cancers, novel compounds endowed with a histone deacetylase (HDAC) inhibitory activity are an attractive therapeutic approach. In this review, we discu...

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Bibliographic Details
Main Authors: Noriyuki Takai, Hisashi Narahara
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2010/923824
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