Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study
Objective. Evaluation of the pruritus features in children with end-stage renal disease (ESRD) who underwent dialysis at an academic tertiary pediatric dialysis center. Methods. This cross-sectional study was conducted at an academic tertiary pediatric dialysis center, Isfahan, Iran. The reviewed me...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2021/9970321 |
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| author | Mehryar Mehrkash Seyed-javad Golestaneh Yahya Madihi Fatemeh Paknazar Mahdi Hadian Mojtaba Akbari Bahareh Abtahi-Naeini |
| author_facet | Mehryar Mehrkash Seyed-javad Golestaneh Yahya Madihi Fatemeh Paknazar Mahdi Hadian Mojtaba Akbari Bahareh Abtahi-Naeini |
| author_sort | Mehryar Mehrkash |
| collection | DOAJ |
| description | Objective. Evaluation of the pruritus features in children with end-stage renal disease (ESRD) who underwent dialysis at an academic tertiary pediatric dialysis center. Methods. This cross-sectional study was conducted at an academic tertiary pediatric dialysis center, Isfahan, Iran. The reviewed medical records of the children included their characteristics, dialysis properties, and laboratory parameters. The 4-item itch questionnaire was utilized to assess distribution, severity, frequency, and associated sleeping disorders. Results. Thirty ESRD patients with pruritus, including 23 males (76.7%) with a mean age of 11.7±3.64 years, were recruited. The most common cause of CKD was nephronophthisis (23.3%). The median total score of pruritus was 5 (range: 3-15). The distribution score of pruritus was directly correlated with the age (Spearman’s rho=0.42, P=0.02) and serum level of parathyroid hormone (PTH) (Spearman’s rho=0.42, P=0.04). In the reduced multiple logistic regression model, the increasing level of serum calcium was associated with increased odds of having total pruritus score≥5 (OR (odds ratio): 4.5; 95% CI 1.12 to 18.05). In addition, an increase in age for one year was found to be associated with 50% higher odds of having total pruritus score≥5 (OR: 1.5; 95% CI 1.03 to 2.18). Conclusion. Increased level of serum Ca and higher age were associated with increased odds of having more severe pruritus score in children. |
| format | Article |
| id | doaj-art-4dab26f9388f44c983013406e6a84913 |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-4dab26f9388f44c983013406e6a849132025-02-03T01:25:47ZengWileyInternational Journal of Pediatrics1687-97401687-97592021-01-01202110.1155/2021/99703219970321Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional StudyMehryar Mehrkash0Seyed-javad Golestaneh1Yahya Madihi2Fatemeh Paknazar3Mahdi Hadian4Mojtaba Akbari5Bahareh Abtahi-Naeini6Imam Hossein Children’s Hospital and Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non Communicable Disease, Isfahan University of Medical Sciences, Isfahan, IranSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, IranImam Hossein Children’s Hospital and Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non Communicable Disease, Isfahan University of Medical Sciences, Isfahan, IranSocial Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, IranSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, IranPediatric Dermatology Division of Department of Pediatrics, Imam Hossein Children’s Hospital, Isfahan University of Medical Sciences, Isfahan, IranObjective. Evaluation of the pruritus features in children with end-stage renal disease (ESRD) who underwent dialysis at an academic tertiary pediatric dialysis center. Methods. This cross-sectional study was conducted at an academic tertiary pediatric dialysis center, Isfahan, Iran. The reviewed medical records of the children included their characteristics, dialysis properties, and laboratory parameters. The 4-item itch questionnaire was utilized to assess distribution, severity, frequency, and associated sleeping disorders. Results. Thirty ESRD patients with pruritus, including 23 males (76.7%) with a mean age of 11.7±3.64 years, were recruited. The most common cause of CKD was nephronophthisis (23.3%). The median total score of pruritus was 5 (range: 3-15). The distribution score of pruritus was directly correlated with the age (Spearman’s rho=0.42, P=0.02) and serum level of parathyroid hormone (PTH) (Spearman’s rho=0.42, P=0.04). In the reduced multiple logistic regression model, the increasing level of serum calcium was associated with increased odds of having total pruritus score≥5 (OR (odds ratio): 4.5; 95% CI 1.12 to 18.05). In addition, an increase in age for one year was found to be associated with 50% higher odds of having total pruritus score≥5 (OR: 1.5; 95% CI 1.03 to 2.18). Conclusion. Increased level of serum Ca and higher age were associated with increased odds of having more severe pruritus score in children.http://dx.doi.org/10.1155/2021/9970321 |
| spellingShingle | Mehryar Mehrkash Seyed-javad Golestaneh Yahya Madihi Fatemeh Paknazar Mahdi Hadian Mojtaba Akbari Bahareh Abtahi-Naeini Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study International Journal of Pediatrics |
| title | Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study |
| title_full | Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study |
| title_fullStr | Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study |
| title_full_unstemmed | Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study |
| title_short | Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study |
| title_sort | pruritus features in children with end stage renal disease underwent dialysis a cross sectional study |
| url | http://dx.doi.org/10.1155/2021/9970321 |
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