Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India

Introduction Prior studies on public attitudes and awareness of clinical research (CR) in India before the pandemic identified significant knowledge gaps. Thus, we aim to investigate if the pandemic has influenced awareness and attitudes towards CR given the wide mass and social media coverage on dr...

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Main Authors: Jeffrey Pradeep Raj, Suraj Kallarakal Tomy, Amrutha Jose, Aadrika Kashyap, Joseph Varghese Kureethara, Tomy K Kallarakal
Format: Article
Language:English
Published: BMJ Publishing Group 2024-06-01
Series:BMJ Public Health
Online Access:https://bmjpublichealth.bmj.com/content/2/1/e000748.full
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author Jeffrey Pradeep Raj
Suraj Kallarakal Tomy
Amrutha Jose
Aadrika Kashyap
Joseph Varghese Kureethara
Tomy K Kallarakal
author_facet Jeffrey Pradeep Raj
Suraj Kallarakal Tomy
Amrutha Jose
Aadrika Kashyap
Joseph Varghese Kureethara
Tomy K Kallarakal
author_sort Jeffrey Pradeep Raj
collection DOAJ
description Introduction Prior studies on public attitudes and awareness of clinical research (CR) in India before the pandemic identified significant knowledge gaps. Thus, we aim to investigate if the pandemic has influenced awareness and attitudes towards CR given the wide mass and social media coverage on drug/vaccine development process.Methods This was an online survey conducted among young adults enrolled as students in a university in south India between 15 September 2022 and 31 October 2022. Until recently, these students attended online classes from various locations across India, likely reflecting a diverse regional and traditional background. Information regarding their sociodemographic status, awareness and perception about CR was collected and analysed applying the principle of descriptive and inferential statistics.Results A total of N=4796 eligible survey responses were analysed. Approximately, 50% were unfamiliar with CR but 42.4% expressed willingness to participate in a future CR. The significant predictors for a higher favourable perception score were having heard about CR (p<0.001), known exactly what a CR means (p<0.001) and having known anyone who participated in a CR (p<0.001). The significant predictors for willingness to participate in a CR were those living in villages as against those living in cities (p=0.002), belongs to Brahm Govind (BG) Prasad’s socioeconomic status class 1 (p=0.023) or class 4 (p=0.011) as against those in class 5, those who have heard about CR (p=0.023), participated in CR (p<0.001), have known someone participated in a CR (p<0.001) or higher total score of favourable perceptions (p<0.001).Conclusions While there was extensive media coverage on drug/vaccine development processes during the COVID-19 pandemic, significant knowledge gaps and concerns regarding various aspects of CR persisted. Although some individuals showed a positive view of CR and its societal benefits, the overall public awareness remains insufficient.
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spelling doaj-art-4daacb6a1c4643a887668e23a775a1202025-01-28T15:25:10ZengBMJ Publishing GroupBMJ Public Health2753-42942024-06-012110.1136/bmjph-2023-000748Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from IndiaJeffrey Pradeep Raj0Suraj Kallarakal Tomy1Amrutha Jose2Aadrika Kashyap3Joseph Varghese Kureethara4Tomy K Kallarakal5Pharmacology, Kasturba Medical College, Manipal Manipal Academy of Higher Eduction, Manipal, Karnataka, IndiaDepartment of Paediatrics, Manipal Hospitals, Bangalore, Karnataka, IndiaNational Institute of Immunohaematology, Mumbai, Maharashtra, IndiaSeth GS Medical College and KEM Hospital, Mumbai, Maharashtra, IndiaCHRIST (Deemed to be University), Bangalore, Karnataka, IndiaCHRIST (Deemed to be University), Bangalore, Karnataka, IndiaIntroduction Prior studies on public attitudes and awareness of clinical research (CR) in India before the pandemic identified significant knowledge gaps. Thus, we aim to investigate if the pandemic has influenced awareness and attitudes towards CR given the wide mass and social media coverage on drug/vaccine development process.Methods This was an online survey conducted among young adults enrolled as students in a university in south India between 15 September 2022 and 31 October 2022. Until recently, these students attended online classes from various locations across India, likely reflecting a diverse regional and traditional background. Information regarding their sociodemographic status, awareness and perception about CR was collected and analysed applying the principle of descriptive and inferential statistics.Results A total of N=4796 eligible survey responses were analysed. Approximately, 50% were unfamiliar with CR but 42.4% expressed willingness to participate in a future CR. The significant predictors for a higher favourable perception score were having heard about CR (p<0.001), known exactly what a CR means (p<0.001) and having known anyone who participated in a CR (p<0.001). The significant predictors for willingness to participate in a CR were those living in villages as against those living in cities (p=0.002), belongs to Brahm Govind (BG) Prasad’s socioeconomic status class 1 (p=0.023) or class 4 (p=0.011) as against those in class 5, those who have heard about CR (p=0.023), participated in CR (p<0.001), have known someone participated in a CR (p<0.001) or higher total score of favourable perceptions (p<0.001).Conclusions While there was extensive media coverage on drug/vaccine development processes during the COVID-19 pandemic, significant knowledge gaps and concerns regarding various aspects of CR persisted. Although some individuals showed a positive view of CR and its societal benefits, the overall public awareness remains insufficient.https://bmjpublichealth.bmj.com/content/2/1/e000748.full
spellingShingle Jeffrey Pradeep Raj
Suraj Kallarakal Tomy
Amrutha Jose
Aadrika Kashyap
Joseph Varghese Kureethara
Tomy K Kallarakal
Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India
BMJ Public Health
title Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India
title_full Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India
title_fullStr Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India
title_full_unstemmed Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India
title_short Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India
title_sort knowledge and perceptions about clinical research and its ethical conduct among college students from non science background a representative nation wide survey from india
url https://bmjpublichealth.bmj.com/content/2/1/e000748.full
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