Development of Multi-Phase Solid Formation for Dissolution Enhancement of Higher Drug Loading Phase-Separated Melt

The method of Multi-Phase Solid with Shear (MPSwS), which uses shear force to form multi-phase solids, was investigated to evaluate the effect of changing drug loadings on the dissolution performance of API. Dissolution results showed that the dissolution rate monotonically decreased when the drug l...

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Bibliographic Details
Main Authors: Bolor-Uyanga Tumurbaatar, Hiroshi Takiyama
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Journal of Chemical Engineering of Japan
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Online Access:https://www.tandfonline.com/doi/10.1080/00219592.2025.2461078
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