Microchannels Effective Method for the Extraction of Oleuropein Compared with Conventional Methods

Different methods of oleuropein extraction from olive leaf were investigated, including maceration, soxhlet, ultrasonic-assisted extraction, and microchannel. In current research, a response surface methodology (RSM) was used for prediction of the optimal values of parameters affecting the extractio...

Full description

Saved in:
Bibliographic Details
Main Authors: Mahnaz Yasemi, Amir Heydarinasab, Masoud Rahimi, Mehdi Ardjmand
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2017/6594156
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832558650001981440
author Mahnaz Yasemi
Amir Heydarinasab
Masoud Rahimi
Mehdi Ardjmand
author_facet Mahnaz Yasemi
Amir Heydarinasab
Masoud Rahimi
Mehdi Ardjmand
author_sort Mahnaz Yasemi
collection DOAJ
description Different methods of oleuropein extraction from olive leaf were investigated, including maceration, soxhlet, ultrasonic-assisted extraction, and microchannel. In current research, a response surface methodology (RSM) was used for prediction of the optimal values of parameters affecting the extraction of oleuropein through two methods of ultrasound and microchannel. Frequency (F), temperature (T), and power of ultrasound (P) were the parameters which were studied in ultrasound method, but in microchannel system effects of pH and temperature (T), volumetric flow rate ratio of two phases (VR), and contact time (CT) of two phases were optimized. UV detector device at 254 nm was used to recognize oleuropein through comparison of the retention time of the extracts with standard compound in chromatogram. The analysis of extracts was performed using HPLC. Optimum conditions for ultrasound were obtained as follows: F=80 kHz, T = 25°C, and P=100 w. Using these optimum conditions, the extraction of oleuropein was 81.29%. Amount of oleuropein extraction by microchannel method in optimum conditions was 96.29%, which was way more than other applied methods. Microchannel system as a continuous method has many advantages including low solvent consumption, being environment friendly, short time for extraction, and high efficiency.
format Article
id doaj-art-4d9642de4abb46d9b7ce172532bde3fd
institution Kabale University
issn 2090-9063
2090-9071
language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Journal of Chemistry
spelling doaj-art-4d9642de4abb46d9b7ce172532bde3fd2025-02-03T01:31:48ZengWileyJournal of Chemistry2090-90632090-90712017-01-01201710.1155/2017/65941566594156Microchannels Effective Method for the Extraction of Oleuropein Compared with Conventional MethodsMahnaz Yasemi0Amir Heydarinasab1Masoud Rahimi2Mehdi Ardjmand3Department of Chemical Engineering, Science and Research Branch, Islamic Azad University, Tehran, IranDepartment of Chemical Engineering, Science and Research Branch, Islamic Azad University, Tehran, IranCFD Research Center, Department of Chemical Engineering, Razi University, Taghe Bostan, 67149 Kermanshah, IranDepartment of Chemical Engineering, Islamic Azad University, South Tehran Branch, Tehran, IranDifferent methods of oleuropein extraction from olive leaf were investigated, including maceration, soxhlet, ultrasonic-assisted extraction, and microchannel. In current research, a response surface methodology (RSM) was used for prediction of the optimal values of parameters affecting the extraction of oleuropein through two methods of ultrasound and microchannel. Frequency (F), temperature (T), and power of ultrasound (P) were the parameters which were studied in ultrasound method, but in microchannel system effects of pH and temperature (T), volumetric flow rate ratio of two phases (VR), and contact time (CT) of two phases were optimized. UV detector device at 254 nm was used to recognize oleuropein through comparison of the retention time of the extracts with standard compound in chromatogram. The analysis of extracts was performed using HPLC. Optimum conditions for ultrasound were obtained as follows: F=80 kHz, T = 25°C, and P=100 w. Using these optimum conditions, the extraction of oleuropein was 81.29%. Amount of oleuropein extraction by microchannel method in optimum conditions was 96.29%, which was way more than other applied methods. Microchannel system as a continuous method has many advantages including low solvent consumption, being environment friendly, short time for extraction, and high efficiency.http://dx.doi.org/10.1155/2017/6594156
spellingShingle Mahnaz Yasemi
Amir Heydarinasab
Masoud Rahimi
Mehdi Ardjmand
Microchannels Effective Method for the Extraction of Oleuropein Compared with Conventional Methods
Journal of Chemistry
title Microchannels Effective Method for the Extraction of Oleuropein Compared with Conventional Methods
title_full Microchannels Effective Method for the Extraction of Oleuropein Compared with Conventional Methods
title_fullStr Microchannels Effective Method for the Extraction of Oleuropein Compared with Conventional Methods
title_full_unstemmed Microchannels Effective Method for the Extraction of Oleuropein Compared with Conventional Methods
title_short Microchannels Effective Method for the Extraction of Oleuropein Compared with Conventional Methods
title_sort microchannels effective method for the extraction of oleuropein compared with conventional methods
url http://dx.doi.org/10.1155/2017/6594156
work_keys_str_mv AT mahnazyasemi microchannelseffectivemethodfortheextractionofoleuropeincomparedwithconventionalmethods
AT amirheydarinasab microchannelseffectivemethodfortheextractionofoleuropeincomparedwithconventionalmethods
AT masoudrahimi microchannelseffectivemethodfortheextractionofoleuropeincomparedwithconventionalmethods
AT mehdiardjmand microchannelseffectivemethodfortheextractionofoleuropeincomparedwithconventionalmethods