Correlation of High Sensitive C-Reactive Protein with the Extent of Coronary Atherosclerotic Disease
Background and objectives: The inflammatory process of the intima of coronary vessels is significant in the atherosclerotic process. We aimed to evaluate the role of high sensitive C-reactive protein in diagnosing and prognosis of ischemic heart disease and atherosclerosis. Methods: From 2021-202...
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Kurdistan Higher Council Of Medical Specialties
2024-03-01
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| Series: | Advanced Medical Journal |
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| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/376 |
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| author | Saud Sherwan Anwer Nasih Abdulah Gardi |
| author_facet | Saud Sherwan Anwer Nasih Abdulah Gardi |
| author_sort | Saud Sherwan Anwer |
| collection | DOAJ |
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Background and objectives: The inflammatory process of the intima of coronary vessels is significant in the atherosclerotic process. We aimed to evaluate the role of high sensitive C-reactive protein in diagnosing and prognosis of ischemic heart disease and atherosclerosis.
Methods: From 2021-2022, we randomly enrolled 100 patients referred to surgical specialty hospital/ cardiac center in Erbil City (Jan 2021- Jan 2022) for angiography complaining of a chronic coronary syndrome. Blood sampling was taken to measure (high sensitive C-reactive protein). Coronary artery angiography was done, and the extent of atherosclerosis was measured using the Syntax score and clinical syntax score using the calculator from internet site www.syntaxscore.org.
Results: We enrolled 58 males and 42 females; 39% of patients had Diabetes mellitus, 49% had hypertension, 41% were smoker, 18% with peripheral arterial disease, 8% had chronic obstructive disease, and 3% with left primary illness. The study showed a highly significant linear correlation between high sensitive C-reactive protein and syntax score of 15±10.52 and clinical syntax score 26.68±12.17.
Conclusion: The study concluded that a high sensitive C-reactive protein level is a reliable method to independently predict coronary artery disease in ischemic heart disease patients and the extent of severity; these results were not affected by sex category and other risk factors like diabetes mellitus, hypertension, or smoking.
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| format | Article |
| id | doaj-art-4d8bf8a37ffd4bcea61d83e4713655ca |
| institution | OA Journals |
| issn | 2958-8979 2957-3580 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Kurdistan Higher Council Of Medical Specialties |
| record_format | Article |
| series | Advanced Medical Journal |
| spelling | doaj-art-4d8bf8a37ffd4bcea61d83e4713655ca2025-08-20T02:12:59ZengKurdistan Higher Council Of Medical SpecialtiesAdvanced Medical Journal2958-89792957-35802024-03-019110.56056/amj.2024.249Correlation of High Sensitive C-Reactive Protein with the Extent of Coronary Atherosclerotic DiseaseSaud Sherwan Anwer0 Nasih Abdulah Gardi1 MB.Ch.B, MSc cardiology, High diploma candidate in interventional cardiology, College of Medicine, Hawler Medical UniversityIraqi Board in Internal Medicine, I.B.M.S-med, Msc interventional cardiology, Hawler Medical University Background and objectives: The inflammatory process of the intima of coronary vessels is significant in the atherosclerotic process. We aimed to evaluate the role of high sensitive C-reactive protein in diagnosing and prognosis of ischemic heart disease and atherosclerosis. Methods: From 2021-2022, we randomly enrolled 100 patients referred to surgical specialty hospital/ cardiac center in Erbil City (Jan 2021- Jan 2022) for angiography complaining of a chronic coronary syndrome. Blood sampling was taken to measure (high sensitive C-reactive protein). Coronary artery angiography was done, and the extent of atherosclerosis was measured using the Syntax score and clinical syntax score using the calculator from internet site www.syntaxscore.org. Results: We enrolled 58 males and 42 females; 39% of patients had Diabetes mellitus, 49% had hypertension, 41% were smoker, 18% with peripheral arterial disease, 8% had chronic obstructive disease, and 3% with left primary illness. The study showed a highly significant linear correlation between high sensitive C-reactive protein and syntax score of 15±10.52 and clinical syntax score 26.68±12.17. Conclusion: The study concluded that a high sensitive C-reactive protein level is a reliable method to independently predict coronary artery disease in ischemic heart disease patients and the extent of severity; these results were not affected by sex category and other risk factors like diabetes mellitus, hypertension, or smoking. https://amj.khcms.edu.krd/index.php/main/article/view/376AtherosclerosisHigh sensitive C-Reactive proteinIschemic Heart disease |
| spellingShingle | Saud Sherwan Anwer Nasih Abdulah Gardi Correlation of High Sensitive C-Reactive Protein with the Extent of Coronary Atherosclerotic Disease Advanced Medical Journal Atherosclerosis High sensitive C-Reactive protein Ischemic Heart disease |
| title | Correlation of High Sensitive C-Reactive Protein with the Extent of Coronary Atherosclerotic Disease |
| title_full | Correlation of High Sensitive C-Reactive Protein with the Extent of Coronary Atherosclerotic Disease |
| title_fullStr | Correlation of High Sensitive C-Reactive Protein with the Extent of Coronary Atherosclerotic Disease |
| title_full_unstemmed | Correlation of High Sensitive C-Reactive Protein with the Extent of Coronary Atherosclerotic Disease |
| title_short | Correlation of High Sensitive C-Reactive Protein with the Extent of Coronary Atherosclerotic Disease |
| title_sort | correlation of high sensitive c reactive protein with the extent of coronary atherosclerotic disease |
| topic | Atherosclerosis High sensitive C-Reactive protein Ischemic Heart disease |
| url | https://amj.khcms.edu.krd/index.php/main/article/view/376 |
| work_keys_str_mv | AT saudsherwananwer correlationofhighsensitivecreactiveproteinwiththeextentofcoronaryatheroscleroticdisease AT nasihabdulahgardi correlationofhighsensitivecreactiveproteinwiththeextentofcoronaryatheroscleroticdisease |