Outer membrane permeability of Pseudomonas aeruginosa through β-lactams: new evidence on the role of OprD and OpdP porins in antibiotic resistance

ABSTRACT Gram-negative bacteria are a major concern for public health, particularly due to the continuous rise of antibiotic resistance. A major factor that helps the development of resistance is the outer membrane that is essential since it acts as a strong permeability barrier to many antibiotics...

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Main Authors: Francesco Amisano, Paola Mercuri, Steven Fanara, Olivier Verlaine, Patrick Motte, Jean Marie Frère, Marc Hanikenne, Moreno Galleni
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:Microbiology Spectrum
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Online Access:https://journals.asm.org/doi/10.1128/spectrum.00495-24
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