Acanthosis Nigricans in a Patient with Lung Cancer: A Case Report
Some skin lesions may accompany malignancies. Acanthosis nigricans, one such lesion, is a paraneoplastic dermatosis characterized by hyperpigmented and velvety verrucose plaques observed as symetric eruptions. With this report, we aim to present a rare case of concomitant lung cancer and acanthosis...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2010/412159 |
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| author | Duru Serap Sever Özlem Yüceege Melike Dilli Alper Albayrak Aynur Arıkök Ata Türker Sadik Ardıç |
| author_facet | Duru Serap Sever Özlem Yüceege Melike Dilli Alper Albayrak Aynur Arıkök Ata Türker Sadik Ardıç |
| author_sort | Duru Serap |
| collection | DOAJ |
| description | Some skin lesions may accompany malignancies. Acanthosis nigricans, one such lesion, is a paraneoplastic dermatosis characterized by hyperpigmented and velvety verrucose plaques observed as symetric eruptions. With this report, we aim to present a rare case of concomitant lung cancer and acanthosis nigricans. Malignant acanthosis nigricans is most commonly associated with intra-abdominal malignancies. A 65-year-old patient who had hyperpigmented, hypertrophic and symmetric verrucose lesions at the flexor surfaces of the lower and upper extremities, face, palms and the axillary region. Thoracic computed tomography demonstrated a hypodense mass lesion with a dimension of 5×5.5 cm at the center of basal segment bronchi of the left pulmonary lobe. Fiberoptic bronchoscopy showed that the access to the lower left lobe was almost completely obstructed by the endobronchial lesion. The result of the histopathologic examination of the endobronchial tissue biopsy was reported as non-small cell (adenocarcinoma) lung cancer. Result of the histopathologic analysis of the punch biopsy of the skin lesions was reported as acanthosis nigricans .There are no pathognomonic dermatological findings for lung cancer. In conclusion, there are skin lesions that accompany lung cancer and we believe that these should be considered for differential diagnosis. |
| format | Article |
| id | doaj-art-4d6aee0e31e04ea89dec44d00251b0a2 |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-4d6aee0e31e04ea89dec44d00251b0a22025-08-20T02:38:43ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/412159412159Acanthosis Nigricans in a Patient with Lung Cancer: A Case ReportDuru Serap0Sever Özlem1Yüceege Melike2Dilli Alper3Albayrak Aynur4Arıkök Ata Türker5Sadik Ardıç6Dışkapı Yıldırım Bayazıt Education and Reserch Hospital, Chest Diseases Clinic, 06200 Ankara, TurkeyDışkapı Yıldırım Bayazıt Education and Reserch Hospital, Chest Diseases Clinic, 06200 Ankara, TurkeyDışkapı Yıldırım Bayazıt Education and Reserch Hospital, Chest Diseases Clinic, 06200 Ankara, TurkeyDışkapı Yıldırım Bayazıt Education and Reserch Hospital, Radiology, 06200 Ankara, TurkeyDışkapı Yıldırım Bayazıt Education and Reserch Hospital, 2nd Pathology Clinic, 06200 Ankara, TurkeyDışkapı Yıldırım Bayazıt Education and Reserch Hospital, 2nd Pathology Clinic, 06200 Ankara, TurkeyDışkapı Yıldırım Bayazıt Education and Reserch Hospital, Chest Diseases Clinic, 06200 Ankara, TurkeySome skin lesions may accompany malignancies. Acanthosis nigricans, one such lesion, is a paraneoplastic dermatosis characterized by hyperpigmented and velvety verrucose plaques observed as symetric eruptions. With this report, we aim to present a rare case of concomitant lung cancer and acanthosis nigricans. Malignant acanthosis nigricans is most commonly associated with intra-abdominal malignancies. A 65-year-old patient who had hyperpigmented, hypertrophic and symmetric verrucose lesions at the flexor surfaces of the lower and upper extremities, face, palms and the axillary region. Thoracic computed tomography demonstrated a hypodense mass lesion with a dimension of 5×5.5 cm at the center of basal segment bronchi of the left pulmonary lobe. Fiberoptic bronchoscopy showed that the access to the lower left lobe was almost completely obstructed by the endobronchial lesion. The result of the histopathologic examination of the endobronchial tissue biopsy was reported as non-small cell (adenocarcinoma) lung cancer. Result of the histopathologic analysis of the punch biopsy of the skin lesions was reported as acanthosis nigricans .There are no pathognomonic dermatological findings for lung cancer. In conclusion, there are skin lesions that accompany lung cancer and we believe that these should be considered for differential diagnosis.http://dx.doi.org/10.1155/2010/412159 |
| spellingShingle | Duru Serap Sever Özlem Yüceege Melike Dilli Alper Albayrak Aynur Arıkök Ata Türker Sadik Ardıç Acanthosis Nigricans in a Patient with Lung Cancer: A Case Report Case Reports in Medicine |
| title | Acanthosis Nigricans in a Patient with Lung Cancer: A Case Report |
| title_full | Acanthosis Nigricans in a Patient with Lung Cancer: A Case Report |
| title_fullStr | Acanthosis Nigricans in a Patient with Lung Cancer: A Case Report |
| title_full_unstemmed | Acanthosis Nigricans in a Patient with Lung Cancer: A Case Report |
| title_short | Acanthosis Nigricans in a Patient with Lung Cancer: A Case Report |
| title_sort | acanthosis nigricans in a patient with lung cancer a case report |
| url | http://dx.doi.org/10.1155/2010/412159 |
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