Haematologic and Urologic Manifestations of Cryptococcus neoformans

Cryptococcus neoformans classically causes pulmonary and central nervous system (CNS) infection in immunocompromised hosts and can lead to disseminated disease. Two cases of atypical cryptococcal infection are presented—an elderly Human Immunodeficiency Virus- (HIV-) negative male with a urinary sou...

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Main Authors: Jessica Morgan, John Vardanega, Mimi Yue, Ian Gassiep
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2024/2245391
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author Jessica Morgan
John Vardanega
Mimi Yue
Ian Gassiep
author_facet Jessica Morgan
John Vardanega
Mimi Yue
Ian Gassiep
author_sort Jessica Morgan
collection DOAJ
description Cryptococcus neoformans classically causes pulmonary and central nervous system (CNS) infection in immunocompromised hosts and can lead to disseminated disease. Two cases of atypical cryptococcal infection are presented—an elderly Human Immunodeficiency Virus- (HIV-) negative male with a urinary source of infection and a young HIV-positive male with bone marrow infiltration complicated by haemophagocytic lymphohistiocytosis (HLH). A literature review of systemic cryptococcal infections involving the genitourinary tract and bone marrow was performed. These cases highlight the importance of clinicians considering uncommon manifestations of cryptococcal disease.
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spelling doaj-art-4d616b196b9a401d9695460f537a90b02025-02-03T05:56:55ZengWileyCase Reports in Infectious Diseases2090-66332024-01-01202410.1155/2024/2245391Haematologic and Urologic Manifestations of Cryptococcus neoformansJessica Morgan0John Vardanega1Mimi Yue2Ian Gassiep3Infectious DiseasesInfectious DiseasesHaematologyInfectious DiseasesCryptococcus neoformans classically causes pulmonary and central nervous system (CNS) infection in immunocompromised hosts and can lead to disseminated disease. Two cases of atypical cryptococcal infection are presented—an elderly Human Immunodeficiency Virus- (HIV-) negative male with a urinary source of infection and a young HIV-positive male with bone marrow infiltration complicated by haemophagocytic lymphohistiocytosis (HLH). A literature review of systemic cryptococcal infections involving the genitourinary tract and bone marrow was performed. These cases highlight the importance of clinicians considering uncommon manifestations of cryptococcal disease.http://dx.doi.org/10.1155/2024/2245391
spellingShingle Jessica Morgan
John Vardanega
Mimi Yue
Ian Gassiep
Haematologic and Urologic Manifestations of Cryptococcus neoformans
Case Reports in Infectious Diseases
title Haematologic and Urologic Manifestations of Cryptococcus neoformans
title_full Haematologic and Urologic Manifestations of Cryptococcus neoformans
title_fullStr Haematologic and Urologic Manifestations of Cryptococcus neoformans
title_full_unstemmed Haematologic and Urologic Manifestations of Cryptococcus neoformans
title_short Haematologic and Urologic Manifestations of Cryptococcus neoformans
title_sort haematologic and urologic manifestations of cryptococcus neoformans
url http://dx.doi.org/10.1155/2024/2245391
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AT johnvardanega haematologicandurologicmanifestationsofcryptococcusneoformans
AT mimiyue haematologicandurologicmanifestationsofcryptococcusneoformans
AT iangassiep haematologicandurologicmanifestationsofcryptococcusneoformans