Haematologic and Urologic Manifestations of Cryptococcus neoformans

Cryptococcus neoformans classically causes pulmonary and central nervous system (CNS) infection in immunocompromised hosts and can lead to disseminated disease. Two cases of atypical cryptococcal infection are presented—an elderly Human Immunodeficiency Virus- (HIV-) negative male with a urinary sou...

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Bibliographic Details
Main Authors: Jessica Morgan, John Vardanega, Mimi Yue, Ian Gassiep
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2024/2245391
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Summary:Cryptococcus neoformans classically causes pulmonary and central nervous system (CNS) infection in immunocompromised hosts and can lead to disseminated disease. Two cases of atypical cryptococcal infection are presented—an elderly Human Immunodeficiency Virus- (HIV-) negative male with a urinary source of infection and a young HIV-positive male with bone marrow infiltration complicated by haemophagocytic lymphohistiocytosis (HLH). A literature review of systemic cryptococcal infections involving the genitourinary tract and bone marrow was performed. These cases highlight the importance of clinicians considering uncommon manifestations of cryptococcal disease.
ISSN:2090-6633