Ameloblastic Fibroodontoma of the Mandible with Normal Karyotype in a Pediatric Patient
Background. Ameloblastic fibroodontoma (AFO) is a rare mixed odontogenic tumor with epithelial and mesenchymal components. AFO presents as a painless swelling in the mandible or maxilla. Radiographs show a well-defined radiolucent area containing various amounts of radiopaque material of irregular s...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2012/969687 |
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| author | Esther Manor Elena Kan Lipa Bodner |
| author_facet | Esther Manor Elena Kan Lipa Bodner |
| author_sort | Esther Manor |
| collection | DOAJ |
| description | Background. Ameloblastic fibroodontoma (AFO) is a rare mixed odontogenic tumor with epithelial and mesenchymal components. AFO presents as a painless swelling in the mandible or maxilla. Radiographs show a well-defined radiolucent area containing various amounts of radiopaque material of irregular size and form. The common treatment is enucleation. It is not an aggressive tumor but recurrence and malignant transformation are possible. Methods. An AFO of the mandible of a 3-year-old female is reported. Panoramic radiograph and CT scan revealed a unilocular lesion with radiopaque center and radiolucent margins. Enucleation was performed with a good outcome. Results. Histopathology was a classic AFO. The karyotype was normal. No recurrence was noted at 12 months. Conclusions. As it is a benign tumor with low recurrence rate, conservative surgery is the treatment of choice. As malignant transformation to ameloblastic fibrosarcoma or ameloblastic odontosarcoma is possible despite the normal karyotype, long-term followup is recommended. |
| format | Article |
| id | doaj-art-4d5428178cc442108b29f39141bd9869 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-4d5428178cc442108b29f39141bd98692025-02-03T01:28:25ZengWileyCase Reports in Dentistry2090-64472090-64552012-01-01201210.1155/2012/969687969687Ameloblastic Fibroodontoma of the Mandible with Normal Karyotype in a Pediatric PatientEsther Manor0Elena Kan1Lipa Bodner2Institute of Human Genetics, Soroka Medical Center, and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, IsraelDepartment of Pathology, Soroka Medical Center, and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, IsraelDepartment of Oral and Maxillofacial Surgery, Soroka Medical Center, and Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva 84105, IsraelBackground. Ameloblastic fibroodontoma (AFO) is a rare mixed odontogenic tumor with epithelial and mesenchymal components. AFO presents as a painless swelling in the mandible or maxilla. Radiographs show a well-defined radiolucent area containing various amounts of radiopaque material of irregular size and form. The common treatment is enucleation. It is not an aggressive tumor but recurrence and malignant transformation are possible. Methods. An AFO of the mandible of a 3-year-old female is reported. Panoramic radiograph and CT scan revealed a unilocular lesion with radiopaque center and radiolucent margins. Enucleation was performed with a good outcome. Results. Histopathology was a classic AFO. The karyotype was normal. No recurrence was noted at 12 months. Conclusions. As it is a benign tumor with low recurrence rate, conservative surgery is the treatment of choice. As malignant transformation to ameloblastic fibrosarcoma or ameloblastic odontosarcoma is possible despite the normal karyotype, long-term followup is recommended.http://dx.doi.org/10.1155/2012/969687 |
| spellingShingle | Esther Manor Elena Kan Lipa Bodner Ameloblastic Fibroodontoma of the Mandible with Normal Karyotype in a Pediatric Patient Case Reports in Dentistry |
| title | Ameloblastic Fibroodontoma of the Mandible with Normal Karyotype in a Pediatric Patient |
| title_full | Ameloblastic Fibroodontoma of the Mandible with Normal Karyotype in a Pediatric Patient |
| title_fullStr | Ameloblastic Fibroodontoma of the Mandible with Normal Karyotype in a Pediatric Patient |
| title_full_unstemmed | Ameloblastic Fibroodontoma of the Mandible with Normal Karyotype in a Pediatric Patient |
| title_short | Ameloblastic Fibroodontoma of the Mandible with Normal Karyotype in a Pediatric Patient |
| title_sort | ameloblastic fibroodontoma of the mandible with normal karyotype in a pediatric patient |
| url | http://dx.doi.org/10.1155/2012/969687 |
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