Significant Independent Predictors of Vitamin D Deficiency in Inpatients and Outpatients of a Nephrology Unit

Aims. Kidney disease was found to be a major risk factor for vitamin D deficiency in a population study of patients hospitalized. The aims of the study were to describe the prevalence of vitamin D deficiency inpatients and outpatients in a nephrology department during fall and to evaluate effect of...

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Main Authors: Recep Bentli, Hulya Taskapan, Halil Toktaş, Ozkan Ulutas, Adnan Ozkahraman, Melda Comert
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2013/237869
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author Recep Bentli
Hulya Taskapan
Halil Toktaş
Ozkan Ulutas
Adnan Ozkahraman
Melda Comert
author_facet Recep Bentli
Hulya Taskapan
Halil Toktaş
Ozkan Ulutas
Adnan Ozkahraman
Melda Comert
author_sort Recep Bentli
collection DOAJ
description Aims. Kidney disease was found to be a major risk factor for vitamin D deficiency in a population study of patients hospitalized. The aims of the study were to describe the prevalence of vitamin D deficiency inpatients and outpatients in a nephrology department during fall and to evaluate effect of assessing serum 25-hydroxyvitamin D (25(OH)D) levels and previous supplementation of cholecalciferol on vitamin D status. Methods. We studied 280 subjects in total, between October and January. The subjects were recruited from the following two groups: (a) inpatients and (b) outpatients in nephrology unit. We examined previous documentary evidence of vitamin D supplementation of the patients. Results. The prevalence of vitamin D deficiency among these 280 patients was 62,1% (174 patients). Fifty-three patients (18.9%) had severe vitamin D deficiency, 121 patients (43.2%) moderate vitamin D deficiency, and 66 patients (23.6%) vitamin D insufficiency. In logistic regression analysis female gender, not having vitamin D supplementation history, low serum albumin, and low blood urea nitrogen levels were significant independent predictors of vitamin D deficiency while no association of vitamin D deficiency with diabetes mellitus, serum creatinine, eGFR, and being hospitalized was found. Conclusion. Vitamin D deficiency, seems to be an important problem in both inpatients and outpatients of nephrology. Monitoring serum 25(OH)D concentrations regularly and replacement of vitamin D are important. Women in Turkey are at more risk of deficiency and may therefore need to consume higher doses of vitamin D.
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spelling doaj-art-4d1e96c9447c45d7bb340a0649496af62025-02-03T01:21:43ZengWileyInternational Journal of Endocrinology1687-83371687-83452013-01-01201310.1155/2013/237869237869Significant Independent Predictors of Vitamin D Deficiency in Inpatients and Outpatients of a Nephrology UnitRecep Bentli0Hulya Taskapan1Halil Toktaş2Ozkan Ulutas3Adnan Ozkahraman4Melda Comert5Internal Medicine Department, Medical Faculty, Inonu University, Malatya, TurkeyNephrology Department, Medical Faculty, Inonu University, Malatya, TurkeyInternal Medicine Department, Medical Faculty, Inonu University, Malatya, TurkeyNephrology Department, Medical Faculty, Inonu University, Malatya, TurkeyInternal Medicine Department, Medical Faculty, Inonu University, Malatya, TurkeyInternal Medicine Department, Medical Faculty, Inonu University, Malatya, TurkeyAims. Kidney disease was found to be a major risk factor for vitamin D deficiency in a population study of patients hospitalized. The aims of the study were to describe the prevalence of vitamin D deficiency inpatients and outpatients in a nephrology department during fall and to evaluate effect of assessing serum 25-hydroxyvitamin D (25(OH)D) levels and previous supplementation of cholecalciferol on vitamin D status. Methods. We studied 280 subjects in total, between October and January. The subjects were recruited from the following two groups: (a) inpatients and (b) outpatients in nephrology unit. We examined previous documentary evidence of vitamin D supplementation of the patients. Results. The prevalence of vitamin D deficiency among these 280 patients was 62,1% (174 patients). Fifty-three patients (18.9%) had severe vitamin D deficiency, 121 patients (43.2%) moderate vitamin D deficiency, and 66 patients (23.6%) vitamin D insufficiency. In logistic regression analysis female gender, not having vitamin D supplementation history, low serum albumin, and low blood urea nitrogen levels were significant independent predictors of vitamin D deficiency while no association of vitamin D deficiency with diabetes mellitus, serum creatinine, eGFR, and being hospitalized was found. Conclusion. Vitamin D deficiency, seems to be an important problem in both inpatients and outpatients of nephrology. Monitoring serum 25(OH)D concentrations regularly and replacement of vitamin D are important. Women in Turkey are at more risk of deficiency and may therefore need to consume higher doses of vitamin D.http://dx.doi.org/10.1155/2013/237869
spellingShingle Recep Bentli
Hulya Taskapan
Halil Toktaş
Ozkan Ulutas
Adnan Ozkahraman
Melda Comert
Significant Independent Predictors of Vitamin D Deficiency in Inpatients and Outpatients of a Nephrology Unit
International Journal of Endocrinology
title Significant Independent Predictors of Vitamin D Deficiency in Inpatients and Outpatients of a Nephrology Unit
title_full Significant Independent Predictors of Vitamin D Deficiency in Inpatients and Outpatients of a Nephrology Unit
title_fullStr Significant Independent Predictors of Vitamin D Deficiency in Inpatients and Outpatients of a Nephrology Unit
title_full_unstemmed Significant Independent Predictors of Vitamin D Deficiency in Inpatients and Outpatients of a Nephrology Unit
title_short Significant Independent Predictors of Vitamin D Deficiency in Inpatients and Outpatients of a Nephrology Unit
title_sort significant independent predictors of vitamin d deficiency in inpatients and outpatients of a nephrology unit
url http://dx.doi.org/10.1155/2013/237869
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