Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk Samples
β-Cyclodextrins/acrylic acid modified magnetic gelatin was prepared and then employed as the magnetic solid-phase extraction (MSPE) sorbent for extraction of moxidectin in milk samples. Due to the rigidity of hydrophobic cavity of β-cyclodextrins and carboxyl groups of acrylic acid, magnetic composi...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Analytical Methods in Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2016/7862152 |
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| author | Yinzhu Shang Jing Luo Peng Wang Xiaoya Zhao Cheng Ye Shaofei Guo |
| author_facet | Yinzhu Shang Jing Luo Peng Wang Xiaoya Zhao Cheng Ye Shaofei Guo |
| author_sort | Yinzhu Shang |
| collection | DOAJ |
| description | β-Cyclodextrins/acrylic acid modified magnetic gelatin was prepared and then employed as the magnetic solid-phase extraction (MSPE) sorbent for extraction of moxidectin in milk samples. Due to the rigidity of hydrophobic cavity of β-cyclodextrins and carboxyl groups of acrylic acid, magnetic composites are prepared to form a complex with target molecules through various kinds of chemical reactions and then showed excellent extraction performance. This method exhibits the advantages of simplicity of implementation, short extraction time (5 min), low solvent consumption, and high extraction efficiency. A rapid, simple, and effective method for the analysis of moxidectin in milk samples was established by MSPE coupled with liquid chromatography-fluorescence detection. The limit of detection was 0.1 ng·mL−1 and the recoveries from milk samples were in the range of 93.8%–112.5%. The relative standard deviation was not higher than 6.4%. In conclusion, magnetic solid-phase extraction is a simple and robust preconcentration technique that can be coupled to other analytical methods for the quantitative determination of target molecules in complex samples. |
| format | Article |
| id | doaj-art-4d1b734f4c1f4c58a6eb8f0550e01e84 |
| institution | Kabale University |
| issn | 2090-8865 2090-8873 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Analytical Methods in Chemistry |
| spelling | doaj-art-4d1b734f4c1f4c58a6eb8f0550e01e842025-02-03T01:21:51ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732016-01-01201610.1155/2016/78621527862152Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk SamplesYinzhu Shang0Jing Luo1Peng Wang2Xiaoya Zhao3Cheng Ye4Shaofei Guo5Hubei Entry-Exit Inspection and Quarantine Bureau of PRC, Wuhan 430022, ChinaHubei Entry-Exit Inspection and Quarantine Bureau of PRC, Wuhan 430022, ChinaHubei Entry-Exit Inspection and Quarantine Bureau of PRC, Wuhan 430022, ChinaHubei Entry-Exit Inspection and Quarantine Bureau of PRC, Wuhan 430022, ChinaHubei Entry-Exit Inspection and Quarantine Bureau of PRC, Wuhan 430022, ChinaHubei Entry-Exit Inspection and Quarantine Bureau of PRC, Wuhan 430022, Chinaβ-Cyclodextrins/acrylic acid modified magnetic gelatin was prepared and then employed as the magnetic solid-phase extraction (MSPE) sorbent for extraction of moxidectin in milk samples. Due to the rigidity of hydrophobic cavity of β-cyclodextrins and carboxyl groups of acrylic acid, magnetic composites are prepared to form a complex with target molecules through various kinds of chemical reactions and then showed excellent extraction performance. This method exhibits the advantages of simplicity of implementation, short extraction time (5 min), low solvent consumption, and high extraction efficiency. A rapid, simple, and effective method for the analysis of moxidectin in milk samples was established by MSPE coupled with liquid chromatography-fluorescence detection. The limit of detection was 0.1 ng·mL−1 and the recoveries from milk samples were in the range of 93.8%–112.5%. The relative standard deviation was not higher than 6.4%. In conclusion, magnetic solid-phase extraction is a simple and robust preconcentration technique that can be coupled to other analytical methods for the quantitative determination of target molecules in complex samples.http://dx.doi.org/10.1155/2016/7862152 |
| spellingShingle | Yinzhu Shang Jing Luo Peng Wang Xiaoya Zhao Cheng Ye Shaofei Guo Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk Samples Journal of Analytical Methods in Chemistry |
| title | Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk Samples |
| title_full | Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk Samples |
| title_fullStr | Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk Samples |
| title_full_unstemmed | Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk Samples |
| title_short | Magnetic Solid-Phase Extraction Based on β-Cyclodextrins/Acrylic Acid Modified Magnetic Gelatin for Determination of Moxidectin in Milk Samples |
| title_sort | magnetic solid phase extraction based on β cyclodextrins acrylic acid modified magnetic gelatin for determination of moxidectin in milk samples |
| url | http://dx.doi.org/10.1155/2016/7862152 |
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