Lower Limb Ischemia: Aortoiliac Thrombosis Related to Antiphospholipid Syndrome (APS)—Case Report and Review of the Literature
Antiphospholipid syndrome (APS) is recognized as one of the main determinants of hypercoagulable conditions. The literature reports the incidence of this syndrome in a third of patients who underwent surgery for peripheral revascularization. Antiphospholipid antibodies are divided into two categorie...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2013/536971 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560378953859072 |
|---|---|
| author | Arnaldo Toffon Raffaella Piovesan Consolato Francesco Minniti Omar Caruso Paolo Criscenti Sabina Villalta Maurizio Cavallo |
| author_facet | Arnaldo Toffon Raffaella Piovesan Consolato Francesco Minniti Omar Caruso Paolo Criscenti Sabina Villalta Maurizio Cavallo |
| author_sort | Arnaldo Toffon |
| collection | DOAJ |
| description | Antiphospholipid syndrome (APS) is recognized as one of the main determinants of hypercoagulable conditions. The literature reports the incidence of this syndrome in a third of patients who underwent surgery for peripheral revascularization. Antiphospholipid antibodies are divided into two categories in relation to specific diagnostic tests. The first group is called lupus anticoagulant and consists of immunoglobulins that inhibit the phospholipid dependent coagulation tests in vitro. The second group is defined by their ability to conduct the phospholipid in an ELISA test. The occurrence of thrombotic events in patients with systemic erythematosus lupus (SEL) and anticoagulant antibodies was described for the first time in 1963 by Bowie. The discovery of anti-cardiolipin antibodies in antiphospholipid syndrome is due to Harris et al. who described the syndrome. Primitive APS was consequently defined in the absence of further underlying illnesses. In this disease, arterial thrombosis occurs mainly in the brain. Peripheral arteries are affected less frequently. Thrombosis of the great vessels is reported as anecdotal. |
| format | Article |
| id | doaj-art-4d0c823ad4f240148763c6aeb4ed5510 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-4d0c823ad4f240148763c6aeb4ed55102025-02-03T01:27:40ZengWileyCase Reports in Surgery2090-69002090-69192013-01-01201310.1155/2013/536971536971Lower Limb Ischemia: Aortoiliac Thrombosis Related to Antiphospholipid Syndrome (APS)—Case Report and Review of the LiteratureArnaldo Toffon0Raffaella Piovesan1Consolato Francesco Minniti2Omar Caruso3Paolo Criscenti4Sabina Villalta5Maurizio Cavallo6San Lorenzo Hospital UOSD Vascular Surgery, Valdagno, ItalyUniversity of Verona, Vascular Surgery Department, Verona, ItalySan Lorenzo Hospital UOSD Vascular Surgery, Valdagno, ItalyUniversity of Verona, Vascular Surgery Department, Verona, ItalyUniversity of Verona, Vascular Surgery Department, Verona, ItalyCà Foncello Hospital, Internal Medicine Department, Treviso, ItalyUniversity of Verona, Vascular Surgery Department, Verona, ItalyAntiphospholipid syndrome (APS) is recognized as one of the main determinants of hypercoagulable conditions. The literature reports the incidence of this syndrome in a third of patients who underwent surgery for peripheral revascularization. Antiphospholipid antibodies are divided into two categories in relation to specific diagnostic tests. The first group is called lupus anticoagulant and consists of immunoglobulins that inhibit the phospholipid dependent coagulation tests in vitro. The second group is defined by their ability to conduct the phospholipid in an ELISA test. The occurrence of thrombotic events in patients with systemic erythematosus lupus (SEL) and anticoagulant antibodies was described for the first time in 1963 by Bowie. The discovery of anti-cardiolipin antibodies in antiphospholipid syndrome is due to Harris et al. who described the syndrome. Primitive APS was consequently defined in the absence of further underlying illnesses. In this disease, arterial thrombosis occurs mainly in the brain. Peripheral arteries are affected less frequently. Thrombosis of the great vessels is reported as anecdotal.http://dx.doi.org/10.1155/2013/536971 |
| spellingShingle | Arnaldo Toffon Raffaella Piovesan Consolato Francesco Minniti Omar Caruso Paolo Criscenti Sabina Villalta Maurizio Cavallo Lower Limb Ischemia: Aortoiliac Thrombosis Related to Antiphospholipid Syndrome (APS)—Case Report and Review of the Literature Case Reports in Surgery |
| title | Lower Limb Ischemia: Aortoiliac Thrombosis Related to Antiphospholipid Syndrome (APS)—Case Report and Review of the Literature |
| title_full | Lower Limb Ischemia: Aortoiliac Thrombosis Related to Antiphospholipid Syndrome (APS)—Case Report and Review of the Literature |
| title_fullStr | Lower Limb Ischemia: Aortoiliac Thrombosis Related to Antiphospholipid Syndrome (APS)—Case Report and Review of the Literature |
| title_full_unstemmed | Lower Limb Ischemia: Aortoiliac Thrombosis Related to Antiphospholipid Syndrome (APS)—Case Report and Review of the Literature |
| title_short | Lower Limb Ischemia: Aortoiliac Thrombosis Related to Antiphospholipid Syndrome (APS)—Case Report and Review of the Literature |
| title_sort | lower limb ischemia aortoiliac thrombosis related to antiphospholipid syndrome aps case report and review of the literature |
| url | http://dx.doi.org/10.1155/2013/536971 |
| work_keys_str_mv | AT arnaldotoffon lowerlimbischemiaaortoiliacthrombosisrelatedtoantiphospholipidsyndromeapscasereportandreviewoftheliterature AT raffaellapiovesan lowerlimbischemiaaortoiliacthrombosisrelatedtoantiphospholipidsyndromeapscasereportandreviewoftheliterature AT consolatofrancescominniti lowerlimbischemiaaortoiliacthrombosisrelatedtoantiphospholipidsyndromeapscasereportandreviewoftheliterature AT omarcaruso lowerlimbischemiaaortoiliacthrombosisrelatedtoantiphospholipidsyndromeapscasereportandreviewoftheliterature AT paolocriscenti lowerlimbischemiaaortoiliacthrombosisrelatedtoantiphospholipidsyndromeapscasereportandreviewoftheliterature AT sabinavillalta lowerlimbischemiaaortoiliacthrombosisrelatedtoantiphospholipidsyndromeapscasereportandreviewoftheliterature AT mauriziocavallo lowerlimbischemiaaortoiliacthrombosisrelatedtoantiphospholipidsyndromeapscasereportandreviewoftheliterature |