Psychiatric Symptoms in Patients with Focal cortical Degeneration
The psychiatric phenomenology exhibited by a mixed group of patients with focal cortical degeneration (FCD) is described. The diagnosis of FCD was made in the presence of a slowly progressive focal neuropsychological deficit without evidence of infarct or neoplasm. Localized or asymmetric atrophy wa...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
1994-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.3233/BEN-1994-73-407 |
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| _version_ | 1832560178591956992 |
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| author | R. M. Lawrence M. A. Ronca P. Tyrrell M. N. Rossor |
| author_facet | R. M. Lawrence M. A. Ronca P. Tyrrell M. N. Rossor |
| author_sort | R. M. Lawrence |
| collection | DOAJ |
| description | The psychiatric phenomenology exhibited by a mixed group of patients with focal cortical degeneration (FCD) is described. The diagnosis of FCD was made in the presence of a slowly progressive focal neuropsychological deficit without evidence of infarct or neoplasm. Localized or asymmetric atrophy was present on neuroimaging (CT or MRI) and positron emission tomography demonstrated focal hypometabolism or in those assessed later in the disease an area of maximal hypometabolism which correlated with the neuropsychological deficit. FCD patients exhibited prominent obsessive–compulsive behaviour. Obsessive–compulsive features were often repetitive, stereotyped and bizarre and occurred in association with frontal and left temporal atrophy and hypometabolism and were absent in those with predominant posterior cortical pathology. |
| format | Article |
| id | doaj-art-4ce7ab9600be434d811280ce9823b3d8 |
| institution | Kabale University |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 1994-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-4ce7ab9600be434d811280ce9823b3d82025-02-03T01:28:10ZengWileyBehavioural Neurology0953-41801875-85841994-01-0173-415315810.3233/BEN-1994-73-407Psychiatric Symptoms in Patients with Focal cortical DegenerationR. M. Lawrence0M. A. Ronca1P. Tyrrell2M. N. Rossor3National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UKNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UKNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UKNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UKThe psychiatric phenomenology exhibited by a mixed group of patients with focal cortical degeneration (FCD) is described. The diagnosis of FCD was made in the presence of a slowly progressive focal neuropsychological deficit without evidence of infarct or neoplasm. Localized or asymmetric atrophy was present on neuroimaging (CT or MRI) and positron emission tomography demonstrated focal hypometabolism or in those assessed later in the disease an area of maximal hypometabolism which correlated with the neuropsychological deficit. FCD patients exhibited prominent obsessive–compulsive behaviour. Obsessive–compulsive features were often repetitive, stereotyped and bizarre and occurred in association with frontal and left temporal atrophy and hypometabolism and were absent in those with predominant posterior cortical pathology.http://dx.doi.org/10.3233/BEN-1994-73-407 |
| spellingShingle | R. M. Lawrence M. A. Ronca P. Tyrrell M. N. Rossor Psychiatric Symptoms in Patients with Focal cortical Degeneration Behavioural Neurology |
| title | Psychiatric Symptoms in Patients with Focal cortical Degeneration |
| title_full | Psychiatric Symptoms in Patients with Focal cortical Degeneration |
| title_fullStr | Psychiatric Symptoms in Patients with Focal cortical Degeneration |
| title_full_unstemmed | Psychiatric Symptoms in Patients with Focal cortical Degeneration |
| title_short | Psychiatric Symptoms in Patients with Focal cortical Degeneration |
| title_sort | psychiatric symptoms in patients with focal cortical degeneration |
| url | http://dx.doi.org/10.3233/BEN-1994-73-407 |
| work_keys_str_mv | AT rmlawrence psychiatricsymptomsinpatientswithfocalcorticaldegeneration AT maronca psychiatricsymptomsinpatientswithfocalcorticaldegeneration AT ptyrrell psychiatricsymptomsinpatientswithfocalcorticaldegeneration AT mnrossor psychiatricsymptomsinpatientswithfocalcorticaldegeneration |