A dynamic model of CT scans for quantifying doubling time of ground glass opacities using histogram analysis

We quantify a recent five-category CT histogram based classification of ground glass opacities using a dynamic mathematical model for the spatial-temporal evolution of malignant nodules. Our mathematical model takes the form of a spatially structured partial differential equation with a logistic cro...

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Bibliographic Details
Main Authors: József Z. Farkas, Gary T. Smith, Glenn F. Webb
Format: Article
Language:English
Published: AIMS Press 2018-09-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2018055
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Summary:We quantify a recent five-category CT histogram based classification of ground glass opacities using a dynamic mathematical model for the spatial-temporal evolution of malignant nodules. Our mathematical model takes the form of a spatially structured partial differential equation with a logistic crowding term. We present the results of extensive simulations and validate our model using patient data obtained from clinical CT images from patients with benign and malignant lesions.
ISSN:1551-0018