Meningococcal Neonatal Purulent Conjunctivitis/Sepsis and Asymptomatic Carriage of N. meningitidis in Mother’s Vagina and Both Parents’ Nasopharynx
Neonatal conjunctivitis is usually associated with vagina’s infection by Chlamydia sp., N. gonorrhoeae, and/or other bacteria during delivery. Meningococcal neonatal conjunctivitis is an extremely rare disease. We report a case of neonatal meningococcal sepsis/conjunctivitis and asymptomatic carriag...
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| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2017/6132857 |
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| author | Enrique Chacon-Cruz Jorge Arturo Alvelais-Palacios Jaime Alfonso Rodriguez-Valencia Erika Zoe Lopatynsky-Reyes Maria Luisa Volker-Soberanes Rosa Maria Rivas-Landeros |
| author_facet | Enrique Chacon-Cruz Jorge Arturo Alvelais-Palacios Jaime Alfonso Rodriguez-Valencia Erika Zoe Lopatynsky-Reyes Maria Luisa Volker-Soberanes Rosa Maria Rivas-Landeros |
| author_sort | Enrique Chacon-Cruz |
| collection | DOAJ |
| description | Neonatal conjunctivitis is usually associated with vagina’s infection by Chlamydia sp., N. gonorrhoeae, and/or other bacteria during delivery. Meningococcal neonatal conjunctivitis is an extremely rare disease. We report a case of neonatal meningococcal sepsis/conjunctivitis and asymptomatic carriage of N. meningitidis from both parents (vagina and nasopharynx). As part of our active surveillance for meningococcal disease at the Tijuana General Hospital (TGH), Mexico, we identified a 3-day-old newborn with meningococcal conjunctivitis and sepsis. The patient had a one-day history of conjunctivitis and poor feeding. Clinical examination confirmed profuse purulent conjunctival discharge, as well as clinical signs and laboratory findings suggestive of bacteraemia. Gram stain from conjunctival exudate revealed intracellular Gram negative diplococci; we presumed the baby had gonorrheal conjunctivitis; however, serogroup Y, N. meningitidis was isolated both from conjunctival exudate and blood. Additionally, isolation of serogroup Y, N. meningitidis was obtained from mother’s vagina and both parents’ nasopharynx. The baby was treated with 7 days of IV ceftriaxone and discharged with no sequelae. |
| format | Article |
| id | doaj-art-4cd69751d06d40c09e85ae1d8ca4bd95 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-4cd69751d06d40c09e85ae1d8ca4bd952025-02-03T01:13:10ZengWileyCase Reports in Infectious Diseases2090-66252090-66332017-01-01201710.1155/2017/61328576132857Meningococcal Neonatal Purulent Conjunctivitis/Sepsis and Asymptomatic Carriage of N. meningitidis in Mother’s Vagina and Both Parents’ NasopharynxEnrique Chacon-Cruz0Jorge Arturo Alvelais-Palacios1Jaime Alfonso Rodriguez-Valencia2Erika Zoe Lopatynsky-Reyes3Maria Luisa Volker-Soberanes4Rosa Maria Rivas-Landeros5Department of Pediatrics, Hospital General de Tijuana, Tijuana, BC, MexicoSchool of Medicine, Universidad Autonoma de Baja California, CISALUD Campus, Tecate, BC, MexicoDepartment of Pediatrics, Hospital General de Tijuana, Tijuana, BC, MexicoDepartment of Pediatrics, Hospital General de Tijuana, Tijuana, BC, MexicoDepartment of Microbiology, Hospital General de Tijuana, Tijuana, BC, MexicoDepartment of Microbiology, Hospital General de Tijuana, Tijuana, BC, MexicoNeonatal conjunctivitis is usually associated with vagina’s infection by Chlamydia sp., N. gonorrhoeae, and/or other bacteria during delivery. Meningococcal neonatal conjunctivitis is an extremely rare disease. We report a case of neonatal meningococcal sepsis/conjunctivitis and asymptomatic carriage of N. meningitidis from both parents (vagina and nasopharynx). As part of our active surveillance for meningococcal disease at the Tijuana General Hospital (TGH), Mexico, we identified a 3-day-old newborn with meningococcal conjunctivitis and sepsis. The patient had a one-day history of conjunctivitis and poor feeding. Clinical examination confirmed profuse purulent conjunctival discharge, as well as clinical signs and laboratory findings suggestive of bacteraemia. Gram stain from conjunctival exudate revealed intracellular Gram negative diplococci; we presumed the baby had gonorrheal conjunctivitis; however, serogroup Y, N. meningitidis was isolated both from conjunctival exudate and blood. Additionally, isolation of serogroup Y, N. meningitidis was obtained from mother’s vagina and both parents’ nasopharynx. The baby was treated with 7 days of IV ceftriaxone and discharged with no sequelae.http://dx.doi.org/10.1155/2017/6132857 |
| spellingShingle | Enrique Chacon-Cruz Jorge Arturo Alvelais-Palacios Jaime Alfonso Rodriguez-Valencia Erika Zoe Lopatynsky-Reyes Maria Luisa Volker-Soberanes Rosa Maria Rivas-Landeros Meningococcal Neonatal Purulent Conjunctivitis/Sepsis and Asymptomatic Carriage of N. meningitidis in Mother’s Vagina and Both Parents’ Nasopharynx Case Reports in Infectious Diseases |
| title | Meningococcal Neonatal Purulent Conjunctivitis/Sepsis and Asymptomatic Carriage of N. meningitidis in Mother’s Vagina and Both Parents’ Nasopharynx |
| title_full | Meningococcal Neonatal Purulent Conjunctivitis/Sepsis and Asymptomatic Carriage of N. meningitidis in Mother’s Vagina and Both Parents’ Nasopharynx |
| title_fullStr | Meningococcal Neonatal Purulent Conjunctivitis/Sepsis and Asymptomatic Carriage of N. meningitidis in Mother’s Vagina and Both Parents’ Nasopharynx |
| title_full_unstemmed | Meningococcal Neonatal Purulent Conjunctivitis/Sepsis and Asymptomatic Carriage of N. meningitidis in Mother’s Vagina and Both Parents’ Nasopharynx |
| title_short | Meningococcal Neonatal Purulent Conjunctivitis/Sepsis and Asymptomatic Carriage of N. meningitidis in Mother’s Vagina and Both Parents’ Nasopharynx |
| title_sort | meningococcal neonatal purulent conjunctivitis sepsis and asymptomatic carriage of n meningitidis in mother s vagina and both parents nasopharynx |
| url | http://dx.doi.org/10.1155/2017/6132857 |
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