ECM-Regulator timp Is Required for Stem Cell Niche Organization and Cyst Production in the Drosophila Ovary.

ECM-Regulator timp Is Required for Stem Cell Niche Organization and Cyst Production in the Drosophila Ovary.

The extracellular matrix (ECM) is a pivotal component adult tissues and of many tissue-specific stem cell niches. It provides structural support and regulates niche signaling during tissue maintenance and regeneration. In many tissues, ECM remodeling depends on the regulation of MMP (matrix metallop...

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Main Authors: John R Pearson, Federico Zurita, Laura Tomás-Gallardo, Alfonsa Díaz-Torres, María Del Carmen Díaz de la Loza, Kristian Franze, María D Martín-Bermudo, Acaimo González-Reyes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005763&type=printable
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