Advances in the treatment of glioma-related signaling pathways and mechanisms by metformin

Advances in the treatment of glioma-related signaling pathways and mechanisms by metformin

Metformin (MET) is a commonly used drug for the treatment of type 2 diabetes in the department of endocrinology. In recent years, due to the few clinically effective treatment options including glioma, some scholars have proposed the possibility of metformin in the treatment of glioma, and studies h...

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Main Authors: Xingyuan Ma, Chao Sun, Xiao Ding, Yuhang Zhang, Tingzhen Deng, Yatao Wang, Haijun Yang, Ruiwen Ding, Haotian Li, Dawen Wang, Maohua Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
metformin
glioma
ferroptosis
oxidative stress
AMPK signaling pathway
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1482050/full
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