Prevalence of TB-related symptoms and self-reported disability among adult TB survivors
BACKGROUND: Growing evidence suggests that post-TB-related morbidity occurs often among TB survivors, but there is limited epidemiological data on the burden of symptoms and disability after successful completion of treatment. We evaluated the prevalence of TB-related symptoms, self-reported disabil...
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International Union Against Tuberculosis and Lung Disease (The Union)
2024-12-01
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| Series: | IJTLD Open |
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| author | A.K. McDonald D. Nakkonde P. Kaggwa S. Zalwango A. Joseph E. Buregyeya J.N. Sekandi |
| author_facet | A.K. McDonald D. Nakkonde P. Kaggwa S. Zalwango A. Joseph E. Buregyeya J.N. Sekandi |
| author_sort | A.K. McDonald |
| collection | DOAJ |
| description | BACKGROUND: Growing evidence suggests that post-TB-related morbidity occurs often among TB survivors, but there is limited epidemiological data on the burden of symptoms and disability after successful completion of treatment. We evaluated the prevalence of TB-related symptoms, self-reported disability, and factors associated with disability among adult TB survivors who recently completed treatment in Uganda. METHODS: Between January 2022 and October 2023, we conducted a study of adults who completed treatment for drug-susceptible TB in Kampala, Uganda. We collected data on demographics, TB-related symptoms, HIV status, and disability measured using the World Health Organization Disability Assessment Schedule (WHODAS 2.0). RESULTS: Of the 200 participants, the median age was 33.0 years (IQR 26–44.5); 52.5% were male, and 23% were HIV-infected. The prevalence of TB symptoms was 58%, and self-reported disability was 83.5%. Factors significantly associated with disability were having completed treatment within the last 6–8 months and experiencing TB symptoms (aOR 2.87, P = 0.04; and aOR 2.51, P = 0.03, respectively), after adjusting for age, sex and HIV status. CONCLUSIONS: TB-related symptoms and self-reporting of any disability were highly prevalent in the study population. There is a need for further longitudinal evaluation and considerations to expand the continuum of care and support to improve the quality of life for TB survivors post-TB treatment |
| format | Article |
| id | doaj-art-4c9922f3695a47c5bc1dc7e74e009234 |
| institution | Kabale University |
| issn | 3005-7590 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | International Union Against Tuberculosis and Lung Disease (The Union) |
| record_format | Article |
| series | IJTLD Open |
| spelling | doaj-art-4c9922f3695a47c5bc1dc7e74e0092342025-01-23T13:29:23ZengInternational Union Against Tuberculosis and Lung Disease (The Union)IJTLD Open3005-75902024-12-0111254054610.5588/ijtldopen.24.01413Prevalence of TB-related symptoms and self-reported disability among adult TB survivorsA.K. McDonald0D. Nakkonde1P. Kaggwa2S. Zalwango3A. Joseph4E. Buregyeya5J.N. Sekandi6College of Public Health, Global Health Institute, University of Georgia, Athens, GA, USA;Makerere University, School of Public Health, College of Health Sciences, Kampala, Uganda;College of Public Health, Global Health Institute, University of Georgia, Athens, GA, USA;Makerere University, School of Public Health, College of Health Sciences, Kampala, Uganda;College of Public Health, Global Health Institute, University of Georgia, Athens, GA, USA;Makerere University, School of Public Health, College of Health Sciences, Kampala, Uganda;College of Public Health, Global Health Institute, University of Georgia, Athens, GA, USA;BACKGROUND: Growing evidence suggests that post-TB-related morbidity occurs often among TB survivors, but there is limited epidemiological data on the burden of symptoms and disability after successful completion of treatment. We evaluated the prevalence of TB-related symptoms, self-reported disability, and factors associated with disability among adult TB survivors who recently completed treatment in Uganda. METHODS: Between January 2022 and October 2023, we conducted a study of adults who completed treatment for drug-susceptible TB in Kampala, Uganda. We collected data on demographics, TB-related symptoms, HIV status, and disability measured using the World Health Organization Disability Assessment Schedule (WHODAS 2.0). RESULTS: Of the 200 participants, the median age was 33.0 years (IQR 26–44.5); 52.5% were male, and 23% were HIV-infected. The prevalence of TB symptoms was 58%, and self-reported disability was 83.5%. Factors significantly associated with disability were having completed treatment within the last 6–8 months and experiencing TB symptoms (aOR 2.87, P = 0.04; and aOR 2.51, P = 0.03, respectively), after adjusting for age, sex and HIV status. CONCLUSIONS: TB-related symptoms and self-reporting of any disability were highly prevalent in the study population. There is a need for further longitudinal evaluation and considerations to expand the continuum of care and support to improve the quality of life for TB survivors post-TB treatmenthttps://www.ingentaconnect.com/contentone/iuatld/ijtldo/2024/00000001/00000012/art00003tuberculosispost-tb treatmenttb-associated disabilitypost-tb morbiditytb survivorsugandalow-income settings |
| spellingShingle | A.K. McDonald D. Nakkonde P. Kaggwa S. Zalwango A. Joseph E. Buregyeya J.N. Sekandi Prevalence of TB-related symptoms and self-reported disability among adult TB survivors IJTLD Open tuberculosis post-tb treatment tb-associated disability post-tb morbidity tb survivors uganda low-income settings |
| title | Prevalence of TB-related symptoms and self-reported disability among adult TB survivors |
| title_full | Prevalence of TB-related symptoms and self-reported disability among adult TB survivors |
| title_fullStr | Prevalence of TB-related symptoms and self-reported disability among adult TB survivors |
| title_full_unstemmed | Prevalence of TB-related symptoms and self-reported disability among adult TB survivors |
| title_short | Prevalence of TB-related symptoms and self-reported disability among adult TB survivors |
| title_sort | prevalence of tb related symptoms and self reported disability among adult tb survivors |
| topic | tuberculosis post-tb treatment tb-associated disability post-tb morbidity tb survivors uganda low-income settings |
| url | https://www.ingentaconnect.com/contentone/iuatld/ijtldo/2024/00000001/00000012/art00003 |
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