Synergistic potential of bone marrow mesenchymal stem cells and miR181-a combinational therapy against multiple sclerosis

Synergistic potential of bone marrow mesenchymal stem cells and miR181-a combinational therapy against multiple sclerosis

Abstract Background Multiple sclerosis (MS) is a progressive autoimmune disease characterized by massive inflammatory infiltration, demyelination, and subsequent axonal injury and neuronal damage in the central nervous system (CNS). The etiology of MS remains unclear and there is not yet a definitiv...

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Main Authors: Xin Xiu, Sijia Chen, Yumei Liu, Bo Sun, Hulun Li, Sifan Zhang, Xixi Yang, Yu Wei, Xichen Peng, Yan Wang, Yanping Wang, Junfeng Wu, Yao Zhang, Lili Mu, Qingfei Kong, Xijun Liu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Stem Cell Research & Therapy
Subjects:
Multiple sclerosis
Bone marrow mesenchymal stem cells
MiR181-a
B cells
T cells
Online Access:https://doi.org/10.1186/s13287-025-04401-7
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