Secondary Immunodeficiency
Abstract The field of medicine is constantly changing and, as healthcare providers, we are fortunate to be practicing in a time when patients are living longer and novel therapeutic options continue to evolve. However, these new advances may be associated with adverse effects that practitioners need...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-01-01
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| Series: | Allergy, Asthma & Clinical Immunology |
| Online Access: | https://doi.org/10.1186/s13223-024-00925-4 |
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| _version_ | 1832571580037726208 |
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| author | Persia Pourshahnazari Stephen D. Betschel Vy. H. D. Kim Susan Waserman Rongbo Zhu Harold Kim |
| author_facet | Persia Pourshahnazari Stephen D. Betschel Vy. H. D. Kim Susan Waserman Rongbo Zhu Harold Kim |
| author_sort | Persia Pourshahnazari |
| collection | DOAJ |
| description | Abstract The field of medicine is constantly changing and, as healthcare providers, we are fortunate to be practicing in a time when patients are living longer and novel therapeutic options continue to evolve. However, these new advances may be associated with adverse effects that practitioners need to be aware of. Some of these impair the immune system leading to secondary immunodeficiencies (SID) that increase host susceptibility to infections and other complications. The causes and consequences of these SID are extremely broad, and a detailed review is beyond the scope of this article. The goal of this primer is to provide a general overview and understanding of common conditions and therapies leading to SID, as well as a guide to the assessment and management of patients with SID. |
| format | Article |
| id | doaj-art-4c6f8b387b86439b86bb3d17049223d0 |
| institution | Kabale University |
| issn | 1710-1492 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Allergy, Asthma & Clinical Immunology |
| spelling | doaj-art-4c6f8b387b86439b86bb3d17049223d02025-02-02T12:29:18ZengBMCAllergy, Asthma & Clinical Immunology1710-14922025-01-0120S311010.1186/s13223-024-00925-4Secondary ImmunodeficiencyPersia Pourshahnazari0Stephen D. Betschel1Vy. H. D. Kim2Susan Waserman3Rongbo Zhu4Harold Kim5Division of Allergy and Immunology, Department of Medicine, University of British ColumbiaDivision of Allergy and Immunology, Department of Medicine, St. Michael’s Hospital, University of TorontoDivision of Immunology and Allergy, Hospital for Sick ChildrenDivision of Clinical Immunology and Allergy, Department of Medicine, McMaster UniversityDivision of Clinical Immunology and Allergy, Department of Medicine, Western UniversityDivision of Clinical Immunology and Allergy, Department of Medicine, McMaster UniversityAbstract The field of medicine is constantly changing and, as healthcare providers, we are fortunate to be practicing in a time when patients are living longer and novel therapeutic options continue to evolve. However, these new advances may be associated with adverse effects that practitioners need to be aware of. Some of these impair the immune system leading to secondary immunodeficiencies (SID) that increase host susceptibility to infections and other complications. The causes and consequences of these SID are extremely broad, and a detailed review is beyond the scope of this article. The goal of this primer is to provide a general overview and understanding of common conditions and therapies leading to SID, as well as a guide to the assessment and management of patients with SID.https://doi.org/10.1186/s13223-024-00925-4 |
| spellingShingle | Persia Pourshahnazari Stephen D. Betschel Vy. H. D. Kim Susan Waserman Rongbo Zhu Harold Kim Secondary Immunodeficiency Allergy, Asthma & Clinical Immunology |
| title | Secondary Immunodeficiency |
| title_full | Secondary Immunodeficiency |
| title_fullStr | Secondary Immunodeficiency |
| title_full_unstemmed | Secondary Immunodeficiency |
| title_short | Secondary Immunodeficiency |
| title_sort | secondary immunodeficiency |
| url | https://doi.org/10.1186/s13223-024-00925-4 |
| work_keys_str_mv | AT persiapourshahnazari secondaryimmunodeficiency AT stephendbetschel secondaryimmunodeficiency AT vyhdkim secondaryimmunodeficiency AT susanwaserman secondaryimmunodeficiency AT rongbozhu secondaryimmunodeficiency AT haroldkim secondaryimmunodeficiency |