Tracking the Prevalence of Antibiotic Resistance in <i>Enterococcus</i> Within the Spanish Poultry Industry: Insights from a One Health Approach
<b>Background</b>/<b>Objectives</b>: Antimicrobial resistance (AMR) in <i>Enterococcus</i> species from poultry production represents a significant public health threat due to the potential transmission of AMR through the food chain. This study aimed to examine th...
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MDPI AG
2024-12-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/14/1/16 |
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| author | Josep Garcia-Llorens Isaac Monroy Jan Torres-Boncompte Jose M. Soriano Pablo Catalá-Gregori Sandra Sevilla-Navarro |
| author_facet | Josep Garcia-Llorens Isaac Monroy Jan Torres-Boncompte Jose M. Soriano Pablo Catalá-Gregori Sandra Sevilla-Navarro |
| author_sort | Josep Garcia-Llorens |
| collection | DOAJ |
| description | <b>Background</b>/<b>Objectives</b>: Antimicrobial resistance (AMR) in <i>Enterococcus</i> species from poultry production represents a significant public health threat due to the potential transmission of AMR through the food chain. This study aimed to examine the relative prevalence, resistance patterns, and mannitol fermentation capacity of <i>Enterococcus</i> isolates from various poultry production systems in Spain over a seven-year period (2017–2023). <b>Methods</b>: A total of 215 <i>Enterococcus</i> isolates were analyzed. Phenotypic assessments were conducted to determine resistance rates and metabolic capacities, while genotypic characterization focused on detecting vancomycin-resistance genes (<i>vanA</i>, <i>vanB</i>, <i>vanC</i>, and <i>vanD</i>). <b>Results</b>: <i>Enterococcus faecalis</i> (62.3%) and <i>Enterococcus faecium</i> (29.77%) were the predominant species, primarily isolated from broilers (74.88%), with the highest frequency observed in one-week-old chicks (31.16%). High resistance rates to tetracyclines and streptogramins were identified, while resistance to vancomycin (0.47%) and tigecycline (3.03%) was low. Interestingly, a significant reduction in tetracyclines resistance was shown in this period for <i>Enterococcus faecalis</i> (from 100% to 70% (2017–2023) and <i>Enterococcus faecium</i> (from 100% to 40% (2018–2023)). Multidrug resistance (MDR) was detected in 26.98% of isolates. Mannitol fermentation tests revealed high metabolic capacity in <i>Enterococcus faecalis</i> (99.25%) and <i>Enterococcus faecium</i> (96.88%), associated with adaptability and virulence potential. Genotypic analysis showed a very low prevalence of <i>vanB</i> and <i>vanC</i> genes. <b>Conclusions</b>: These findings highlight the critical need for targeted surveillance and intervention strategies in poultry production to mitigate the risks posed by MDR <i>Enterococcus</i> to public health. |
| format | Article |
| id | doaj-art-4c66c9128c4744a49b3b9cc5bbeaaaf7 |
| institution | Kabale University |
| issn | 2079-6382 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj-art-4c66c9128c4744a49b3b9cc5bbeaaaf72025-01-24T13:18:33ZengMDPI AGAntibiotics2079-63822024-12-011411610.3390/antibiotics14010016Tracking the Prevalence of Antibiotic Resistance in <i>Enterococcus</i> Within the Spanish Poultry Industry: Insights from a One Health ApproachJosep Garcia-Llorens0Isaac Monroy1Jan Torres-Boncompte2Jose M. Soriano3Pablo Catalá-Gregori4Sandra Sevilla-Navarro5Centro de Calidad Avícola y Alimentación Animal de la Comunidad Valenciana (CECAV), 12539 Alquerias del Niño Perdido, SpainCentro de Calidad Avícola y Alimentación Animal de la Comunidad Valenciana (CECAV), 12539 Alquerias del Niño Perdido, SpainCentro de Calidad Avícola y Alimentación Animal de la Comunidad Valenciana (CECAV), 12539 Alquerias del Niño Perdido, SpainFood & Health Lab, Institute of Materials Science, University of Valencia, 46980 Valencia, SpainCentro de Calidad Avícola y Alimentación Animal de la Comunidad Valenciana (CECAV), 12539 Alquerias del Niño Perdido, SpainCentro de Calidad Avícola y Alimentación Animal de la Comunidad Valenciana (CECAV), 12539 Alquerias del Niño Perdido, Spain<b>Background</b>/<b>Objectives</b>: Antimicrobial resistance (AMR) in <i>Enterococcus</i> species from poultry production represents a significant public health threat due to the potential transmission of AMR through the food chain. This study aimed to examine the relative prevalence, resistance patterns, and mannitol fermentation capacity of <i>Enterococcus</i> isolates from various poultry production systems in Spain over a seven-year period (2017–2023). <b>Methods</b>: A total of 215 <i>Enterococcus</i> isolates were analyzed. Phenotypic assessments were conducted to determine resistance rates and metabolic capacities, while genotypic characterization focused on detecting vancomycin-resistance genes (<i>vanA</i>, <i>vanB</i>, <i>vanC</i>, and <i>vanD</i>). <b>Results</b>: <i>Enterococcus faecalis</i> (62.3%) and <i>Enterococcus faecium</i> (29.77%) were the predominant species, primarily isolated from broilers (74.88%), with the highest frequency observed in one-week-old chicks (31.16%). High resistance rates to tetracyclines and streptogramins were identified, while resistance to vancomycin (0.47%) and tigecycline (3.03%) was low. Interestingly, a significant reduction in tetracyclines resistance was shown in this period for <i>Enterococcus faecalis</i> (from 100% to 70% (2017–2023) and <i>Enterococcus faecium</i> (from 100% to 40% (2018–2023)). Multidrug resistance (MDR) was detected in 26.98% of isolates. Mannitol fermentation tests revealed high metabolic capacity in <i>Enterococcus faecalis</i> (99.25%) and <i>Enterococcus faecium</i> (96.88%), associated with adaptability and virulence potential. Genotypic analysis showed a very low prevalence of <i>vanB</i> and <i>vanC</i> genes. <b>Conclusions</b>: These findings highlight the critical need for targeted surveillance and intervention strategies in poultry production to mitigate the risks posed by MDR <i>Enterococcus</i> to public health.https://www.mdpi.com/2079-6382/14/1/16<i>Enterococcus</i>antimicrobial resistancesurveillanceone healthpoultry |
| spellingShingle | Josep Garcia-Llorens Isaac Monroy Jan Torres-Boncompte Jose M. Soriano Pablo Catalá-Gregori Sandra Sevilla-Navarro Tracking the Prevalence of Antibiotic Resistance in <i>Enterococcus</i> Within the Spanish Poultry Industry: Insights from a One Health Approach Antibiotics <i>Enterococcus</i> antimicrobial resistance surveillance one health poultry |
| title | Tracking the Prevalence of Antibiotic Resistance in <i>Enterococcus</i> Within the Spanish Poultry Industry: Insights from a One Health Approach |
| title_full | Tracking the Prevalence of Antibiotic Resistance in <i>Enterococcus</i> Within the Spanish Poultry Industry: Insights from a One Health Approach |
| title_fullStr | Tracking the Prevalence of Antibiotic Resistance in <i>Enterococcus</i> Within the Spanish Poultry Industry: Insights from a One Health Approach |
| title_full_unstemmed | Tracking the Prevalence of Antibiotic Resistance in <i>Enterococcus</i> Within the Spanish Poultry Industry: Insights from a One Health Approach |
| title_short | Tracking the Prevalence of Antibiotic Resistance in <i>Enterococcus</i> Within the Spanish Poultry Industry: Insights from a One Health Approach |
| title_sort | tracking the prevalence of antibiotic resistance in i enterococcus i within the spanish poultry industry insights from a one health approach |
| topic | <i>Enterococcus</i> antimicrobial resistance surveillance one health poultry |
| url | https://www.mdpi.com/2079-6382/14/1/16 |
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