A SARS‐CoV‐2 EG.5 mRNA vaccine induces a broad‐spectrum immune response in mice

A SARS‐CoV‐2 EG.5 mRNA vaccine induces a broad‐spectrum immune response in mice

Abstract The emerging of emergent SARS‐CoV‐2 subvariants has reduced the protective efficacy of COVID‐19 vaccines. Therefore, novel COVID‐19 vaccines targeting these emergent variants are needed. We designed and prepared CoV072, an mRNA‐based vaccine against SARS‐CoV‐2 Omicron (EG.5) and other emerg...

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Main Authors: Hongyu Wang, Qinhua Peng, Xinxian Dai, Zhifang Ying, Xiaohong Wu, Xinyu Liu, Hongshan Xu, Jia Li, Leitai Shi, Jingjing Liu, Yunpeng Wang, Danhua Zhao, Yanqiu Huang, Lihong Yang, Ren Yang, Guangzhi Yue, Yue Suo, Qiang Ye, Shouchun Cao, Yuhua Li
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:MedComm
Subjects:
immunization strategies
immunogenicity
mRNA‐based vaccines
SARS‐CoV‐2 variants
Online Access:https://doi.org/10.1002/mco2.779
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