Changes in the transcriptome of the prefrontal cortex of OXYS rats as the signs of Alzheimer’s disease development

Changes in the transcriptome of the prefrontal cortex of OXYS rats as the signs of Alzheimer’s disease development

Alzheimer’s disease (AD) is the most prevalent neuro­degenerative disease. It produces atrophic changes in the brain, which cause dementia. The incidence of AD is increasing with increasing life expectancy and gradual aging of the population in developed countries. There are no effective prophylacti...

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Bibliographic Details
Main Authors: N. A. Stefanova, E. E. Korbolina, N. I. Ershov, E. I. Rogaev, N. G. Kolosova
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2015-12-01
Series:Вавиловский журнал генетики и селекции
Subjects:
alzheimer’s disease
oxys rats
brain transcriptome
rna-seq
Online Access:https://vavilov.elpub.ru/jour/article/view/434
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