Evidence of H10N8 influenza virus infection among swine in southern China and its infectivity and transmissibility in swine
Infection with a novel H10N8 influenza virus in humans was first described in China in December 2013, which raised concerns related to public health. This novel virus was subsequently confirmed to have originated from a live poultry market. However, whether this virus can infect other mammals remain...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-01-01
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| Series: | Emerging Microbes and Infections |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2019.1708811 |
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| author | Xinliang Fu Yunmao Huang Bo Fang Yixing Liu Mengkai Cai Ruting Zhong Junming Huang Qi Wenbao Yunbo Tian Guihong Zhang |
| author_facet | Xinliang Fu Yunmao Huang Bo Fang Yixing Liu Mengkai Cai Ruting Zhong Junming Huang Qi Wenbao Yunbo Tian Guihong Zhang |
| author_sort | Xinliang Fu |
| collection | DOAJ |
| description | Infection with a novel H10N8 influenza virus in humans was first described in China in December 2013, which raised concerns related to public health. This novel virus was subsequently confirmed to have originated from a live poultry market. However, whether this virus can infect other mammals remains unclear. In the present study, antibody specific for H10N8 influenza virus was detected in swine herds in southern China during serological monitoring for swine influenza virus. The pathogenicity and transmissibility of this H10N8 influenza virus to swine was examined. The results showed that swine are susceptible to infection with human-origin H10N8 influenza virus, which causes viral shedding, severe tissue lesions, and seroconversion, while infection with avian-origin H10N8 influenza virus causes only seroconversion and no viral shedding. Importantly, human-origin H10N8 influenza virus can inefficiently be transmitted between swine and cause seroconversion through direct contact. This study provides a new perspective regarding the ecology of H10N8 influenza virus and highlights the importance of epidemiological monitoring of the H10N8 influenza virus in different animal species, which will be helpful for preventing and controlling future infections by this virus. |
| format | Article |
| id | doaj-art-4c24fa6b809d4e7a94e4c171987e6dd3 |
| institution | OA Journals |
| issn | 2222-1751 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-4c24fa6b809d4e7a94e4c171987e6dd32025-08-20T02:26:36ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512020-01-0191889410.1080/22221751.2019.1708811Evidence of H10N8 influenza virus infection among swine in southern China and its infectivity and transmissibility in swineXinliang Fu0Yunmao Huang1Bo Fang2Yixing Liu3Mengkai Cai4Ruting Zhong5Junming Huang6Qi Wenbao7Yunbo Tian8Guihong Zhang9College of Veterinary Medicine, South China Agricultural University, Guangzhou, People’s Republic of ChinaCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, People’s Republic of ChinaCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, People’s Republic of ChinaCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, People’s Republic of ChinaCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, People’s Republic of ChinaCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, People’s Republic of ChinaCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, People’s Republic of ChinaCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, People’s Republic of ChinaCollege of Animal Science & Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, People’s Republic of ChinaCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, People’s Republic of ChinaInfection with a novel H10N8 influenza virus in humans was first described in China in December 2013, which raised concerns related to public health. This novel virus was subsequently confirmed to have originated from a live poultry market. However, whether this virus can infect other mammals remains unclear. In the present study, antibody specific for H10N8 influenza virus was detected in swine herds in southern China during serological monitoring for swine influenza virus. The pathogenicity and transmissibility of this H10N8 influenza virus to swine was examined. The results showed that swine are susceptible to infection with human-origin H10N8 influenza virus, which causes viral shedding, severe tissue lesions, and seroconversion, while infection with avian-origin H10N8 influenza virus causes only seroconversion and no viral shedding. Importantly, human-origin H10N8 influenza virus can inefficiently be transmitted between swine and cause seroconversion through direct contact. This study provides a new perspective regarding the ecology of H10N8 influenza virus and highlights the importance of epidemiological monitoring of the H10N8 influenza virus in different animal species, which will be helpful for preventing and controlling future infections by this virus.https://www.tandfonline.com/doi/10.1080/22221751.2019.1708811H10N8influenza virusinfectivitypathogenicitytransmissibility |
| spellingShingle | Xinliang Fu Yunmao Huang Bo Fang Yixing Liu Mengkai Cai Ruting Zhong Junming Huang Qi Wenbao Yunbo Tian Guihong Zhang Evidence of H10N8 influenza virus infection among swine in southern China and its infectivity and transmissibility in swine Emerging Microbes and Infections H10N8 influenza virus infectivity pathogenicity transmissibility |
| title | Evidence of H10N8 influenza virus infection among swine in southern China and its infectivity and transmissibility in swine |
| title_full | Evidence of H10N8 influenza virus infection among swine in southern China and its infectivity and transmissibility in swine |
| title_fullStr | Evidence of H10N8 influenza virus infection among swine in southern China and its infectivity and transmissibility in swine |
| title_full_unstemmed | Evidence of H10N8 influenza virus infection among swine in southern China and its infectivity and transmissibility in swine |
| title_short | Evidence of H10N8 influenza virus infection among swine in southern China and its infectivity and transmissibility in swine |
| title_sort | evidence of h10n8 influenza virus infection among swine in southern china and its infectivity and transmissibility in swine |
| topic | H10N8 influenza virus infectivity pathogenicity transmissibility |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2019.1708811 |
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