Clinical Resolution of Osmotic Demyelination Syndrome following Overcorrection of Severe Hyponatremia
Osmotic Demyelination Syndrome (ODS) occurs after rapid overcorrection of severe chronic hyponatremia usually in those with a predisposition such as chronic alcoholism, malnutrition, or liver disease. Rarely, do patients make a full recovery. We report a case of ODS secondary to overcorrection of se...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2019/1757656 |
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| _version_ | 1832549374317559808 |
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| author | Ruhin Yuridullah Vinod Kumar Sushant Nanavati Monisha Singhal Chandra Chandran |
| author_facet | Ruhin Yuridullah Vinod Kumar Sushant Nanavati Monisha Singhal Chandra Chandran |
| author_sort | Ruhin Yuridullah |
| collection | DOAJ |
| description | Osmotic Demyelination Syndrome (ODS) occurs after rapid overcorrection of severe chronic hyponatremia usually in those with a predisposition such as chronic alcoholism, malnutrition, or liver disease. Rarely, do patients make a full recovery. We report a case of ODS secondary to overcorrection of severe hyponatremia with pathognomonic clinical and radiologic signs making a complete neurological recovery. A detailed course of events, review of literature, and optimal and aggressive management strategies are discussed. There is some controversy in the literature regarding the prognosis of these patients. Our aim here is to show that, with aggressive therapy and long-term care, recovery is possible in these patients. |
| format | Article |
| id | doaj-art-4c243c2e5a9a431b825f060d56241013 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-4c243c2e5a9a431b825f060d562410132025-02-03T06:11:27ZengWileyCase Reports in Nephrology2090-66412090-665X2019-01-01201910.1155/2019/17576561757656Clinical Resolution of Osmotic Demyelination Syndrome following Overcorrection of Severe HyponatremiaRuhin Yuridullah0Vinod Kumar1Sushant Nanavati2Monisha Singhal3Chandra Chandran4Saint Joseph’s University Medical Center, USASaint Joseph’s University Medical Center, USASaint Joseph’s University Medical Center, USASaint Joseph’s University Medical Center, USASaint Joseph’s University Medical Center, USAOsmotic Demyelination Syndrome (ODS) occurs after rapid overcorrection of severe chronic hyponatremia usually in those with a predisposition such as chronic alcoholism, malnutrition, or liver disease. Rarely, do patients make a full recovery. We report a case of ODS secondary to overcorrection of severe hyponatremia with pathognomonic clinical and radiologic signs making a complete neurological recovery. A detailed course of events, review of literature, and optimal and aggressive management strategies are discussed. There is some controversy in the literature regarding the prognosis of these patients. Our aim here is to show that, with aggressive therapy and long-term care, recovery is possible in these patients.http://dx.doi.org/10.1155/2019/1757656 |
| spellingShingle | Ruhin Yuridullah Vinod Kumar Sushant Nanavati Monisha Singhal Chandra Chandran Clinical Resolution of Osmotic Demyelination Syndrome following Overcorrection of Severe Hyponatremia Case Reports in Nephrology |
| title | Clinical Resolution of Osmotic Demyelination Syndrome following Overcorrection of Severe Hyponatremia |
| title_full | Clinical Resolution of Osmotic Demyelination Syndrome following Overcorrection of Severe Hyponatremia |
| title_fullStr | Clinical Resolution of Osmotic Demyelination Syndrome following Overcorrection of Severe Hyponatremia |
| title_full_unstemmed | Clinical Resolution of Osmotic Demyelination Syndrome following Overcorrection of Severe Hyponatremia |
| title_short | Clinical Resolution of Osmotic Demyelination Syndrome following Overcorrection of Severe Hyponatremia |
| title_sort | clinical resolution of osmotic demyelination syndrome following overcorrection of severe hyponatremia |
| url | http://dx.doi.org/10.1155/2019/1757656 |
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