Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment
A virosome is an innovative hybrid drug delivery system with advantages of both viral and non-viral vectors. Studies have shown that a virosome can carry various biologically active molecules, such as nucleic acids, peptides, proteins and small organic molecules. Targeted drug delivery using virosom...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2015-06-01
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| Series: | Acta Pharmaceutica |
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| Online Access: | https://doi.org/10.1515/acph-2015-0019 |
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| _version_ | 1832572476265070592 |
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| author | Liu Hanqing Tu Zhigang Feng Fan Shi Haifeng Chen Keping Xu Ximing |
| author_facet | Liu Hanqing Tu Zhigang Feng Fan Shi Haifeng Chen Keping Xu Ximing |
| author_sort | Liu Hanqing |
| collection | DOAJ |
| description | A virosome is an innovative hybrid drug delivery system with advantages of both viral and non-viral vectors. Studies have shown that a virosome can carry various biologically active molecules, such as nucleic acids, peptides, proteins and small organic molecules. Targeted drug delivery using virosome-based systems can be achieved through surface modifications of virosomes. A number of virosome- -based prophylactic and therapeutic products with high safety profiles are currently available in the market. Cancer treatment is a big battlefield for virosome-based drug delivery systems. This review provides an overview of the general concept, preparation procedures, working mechanisms, preclinical studies and clinical applications of virosomes in cancer treatment. |
| format | Article |
| id | doaj-art-4c21a5e6a5184a3b8d04b55727a98caf |
| institution | Kabale University |
| issn | 1846-9558 |
| language | English |
| publishDate | 2015-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Pharmaceutica |
| spelling | doaj-art-4c21a5e6a5184a3b8d04b55727a98caf2025-02-02T09:47:34ZengSciendoActa Pharmaceutica1846-95582015-06-0165210511610.1515/acph-2015-0019acph-2015-0019Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatmentLiu Hanqing0Tu Zhigang1Feng Fan2Shi Haifeng3Chen Keping4Xu Ximing5School of Pharmacy, Jiangsu University, Zhenjiang Jiangsu 212013, ChinaInstitute of Life Sciences Jiangsu University, Zhenjiang Jiangsu 212013, ChinaInstitute of Life Sciences Jiangsu University, Zhenjiang Jiangsu 212013, ChinaInstitute of Life Sciences Jiangsu University, Zhenjiang Jiangsu 212013, ChinaInstitute of Life Sciences Jiangsu University, Zhenjiang Jiangsu 212013, ChinaSchool of Pharmacy, Jiangsu University, Zhenjiang Jiangsu 212013, ChinaA virosome is an innovative hybrid drug delivery system with advantages of both viral and non-viral vectors. Studies have shown that a virosome can carry various biologically active molecules, such as nucleic acids, peptides, proteins and small organic molecules. Targeted drug delivery using virosome-based systems can be achieved through surface modifications of virosomes. A number of virosome- -based prophylactic and therapeutic products with high safety profiles are currently available in the market. Cancer treatment is a big battlefield for virosome-based drug delivery systems. This review provides an overview of the general concept, preparation procedures, working mechanisms, preclinical studies and clinical applications of virosomes in cancer treatment.https://doi.org/10.1515/acph-2015-0019virosomedrug delivery systemcancer treatmentcancer vaccine |
| spellingShingle | Liu Hanqing Tu Zhigang Feng Fan Shi Haifeng Chen Keping Xu Ximing Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment Acta Pharmaceutica virosome drug delivery system cancer treatment cancer vaccine |
| title | Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment |
| title_full | Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment |
| title_fullStr | Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment |
| title_full_unstemmed | Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment |
| title_short | Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment |
| title_sort | virosome a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment |
| topic | virosome drug delivery system cancer treatment cancer vaccine |
| url | https://doi.org/10.1515/acph-2015-0019 |
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