Unveiling the therapeutic potential of senescence-related IQGAP2 in pancreatic Cancer through post-GWAS genomic and scRNA-seq analyses

Unveiling the therapeutic potential of senescence-related IQGAP2 in pancreatic Cancer through post-GWAS genomic and scRNA-seq analyses

Abstract Background Pancreatic cancer (PC) is a highly aggressive tumor with a poor prognosis and few treatment options available. While cellular senescence has been linked to the advancement of various cancers, its specific role in PC is not well understood. Method We employed Mendelian randomizati...

Full description

Saved in:
Bibliographic Details
Main Authors: Zilong Bai, Jiale Liang, Yuanhua Nie, Shilong Wang, Dongmin Chang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Pancreatic cancer
IQGAP2
Cellular senescence
Summary-data-based MR
scRNA-seq
Drug target
Online Access:https://doi.org/10.1007/s12672-025-03078-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items