Primary Amoebic Meningoencephalitis in an Iranian Infant

Introduction. Naegleria fowleri, a free living amoeba, can cause devastating and deadly diseases in humans. This is the first report of primary amoebic meningoencephalitis from Iran. Case report. A five-month-old male infant presented with the history of fever and eye gaze for three days, after beg...

Full description

Saved in:
Bibliographic Details
Main Authors: Zahra Movahedi, Mohammad Reza Shokrollahi, Mohammad Aghaali, Hosein Heydari
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/782854
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832548113521311744
author Zahra Movahedi
Mohammad Reza Shokrollahi
Mohammad Aghaali
Hosein Heydari
author_facet Zahra Movahedi
Mohammad Reza Shokrollahi
Mohammad Aghaali
Hosein Heydari
author_sort Zahra Movahedi
collection DOAJ
description Introduction. Naegleria fowleri, a free living amoeba, can cause devastating and deadly diseases in humans. This is the first report of primary amoebic meningoencephalitis from Iran. Case report. A five-month-old male infant presented with the history of fever and eye gaze for three days, after beginning of bacterial meningitis, a plain and contrast CT revealed communicated hydrocephalus. In the repeat of CSF analysis on microscopic examination of wet preparation of CSF, Naegleria Fowleri was seen. Then, Amphotericin B and Rifampin were started. On followup, two months later, the patient was totally asymptomatic. Conclusion. Though occurrence of PAM is rare, this unusual disease has grave prognosis, so infection with free living amoebas must be considered in differential diagnosis of pediatric patients of purulent meningitis without evidence of bacteria on Gram’s stain and imaging findings, nonspecific brain edema on CT or hydrocephalus even without history of contact.
format Article
id doaj-art-4bd23927aad14c81bb3d0d025849ab11
institution Kabale University
issn 1687-9627
1687-9635
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-4bd23927aad14c81bb3d0d025849ab112025-02-03T06:42:07ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/782854782854Primary Amoebic Meningoencephalitis in an Iranian InfantZahra Movahedi0Mohammad Reza Shokrollahi1Mohammad Aghaali2Hosein Heydari3Qom University of Medical Science, Qom, IranQom University of Medical Science, Qom, IranQom University of Medical Science, Qom, IranQom University of Medical Science, Qom, IranIntroduction. Naegleria fowleri, a free living amoeba, can cause devastating and deadly diseases in humans. This is the first report of primary amoebic meningoencephalitis from Iran. Case report. A five-month-old male infant presented with the history of fever and eye gaze for three days, after beginning of bacterial meningitis, a plain and contrast CT revealed communicated hydrocephalus. In the repeat of CSF analysis on microscopic examination of wet preparation of CSF, Naegleria Fowleri was seen. Then, Amphotericin B and Rifampin were started. On followup, two months later, the patient was totally asymptomatic. Conclusion. Though occurrence of PAM is rare, this unusual disease has grave prognosis, so infection with free living amoebas must be considered in differential diagnosis of pediatric patients of purulent meningitis without evidence of bacteria on Gram’s stain and imaging findings, nonspecific brain edema on CT or hydrocephalus even without history of contact.http://dx.doi.org/10.1155/2012/782854
spellingShingle Zahra Movahedi
Mohammad Reza Shokrollahi
Mohammad Aghaali
Hosein Heydari
Primary Amoebic Meningoencephalitis in an Iranian Infant
Case Reports in Medicine
title Primary Amoebic Meningoencephalitis in an Iranian Infant
title_full Primary Amoebic Meningoencephalitis in an Iranian Infant
title_fullStr Primary Amoebic Meningoencephalitis in an Iranian Infant
title_full_unstemmed Primary Amoebic Meningoencephalitis in an Iranian Infant
title_short Primary Amoebic Meningoencephalitis in an Iranian Infant
title_sort primary amoebic meningoencephalitis in an iranian infant
url http://dx.doi.org/10.1155/2012/782854
work_keys_str_mv AT zahramovahedi primaryamoebicmeningoencephalitisinaniranianinfant
AT mohammadrezashokrollahi primaryamoebicmeningoencephalitisinaniranianinfant
AT mohammadaghaali primaryamoebicmeningoencephalitisinaniranianinfant
AT hoseinheydari primaryamoebicmeningoencephalitisinaniranianinfant