Radiographic Findings in Patients with Medication-Related Osteonecrosis of the Jaw
A retrospective study was conducted of the records and panoramic radiographs of 35 patients treated with bisphosphonates (BP) and diagnosed with MRONJ. Panoramic radiography was used for evaluation, by two examiners, the following findings were subject of search: osteolysis (OT), cortical bone erosi...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2017/3190301 |
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| author | Camila Lopes Cardoso Carolina Arrabal Barros Cláudia Curra Luciana Maria Paes da Silva Ramos Fernandes Solange de Oliveira Braga Franzolin Joel Santiago Ferreira Júnior Carlos César De Antoni Marcos Martins Curi |
| author_facet | Camila Lopes Cardoso Carolina Arrabal Barros Cláudia Curra Luciana Maria Paes da Silva Ramos Fernandes Solange de Oliveira Braga Franzolin Joel Santiago Ferreira Júnior Carlos César De Antoni Marcos Martins Curi |
| author_sort | Camila Lopes Cardoso |
| collection | DOAJ |
| description | A retrospective study was conducted of the records and panoramic radiographs of 35 patients treated with bisphosphonates (BP) and diagnosed with MRONJ. Panoramic radiography was used for evaluation, by two examiners, the following findings were subject of search: osteolysis (OT), cortical bone erosion (EC), bone sclerosis focal (FS) and diffuse (DS), bone sequestration (BS), thickening of lamina dura (TD), prominence of the inferior alveolar nerve canal (IAN), persisting alveolar sockets (SK), and the presence of a pathological fracture (PF). Medical information and staging were also recorded in order to correlate with radiographic findings. Bone sclerosis was the most frequent alteration, followed by OT and TD. The mandible was more affected than the maxilla. There was no significant difference between genders or significant correlation between the number of injuries with age and duration of BP usage. Considering the association between the radiographic findings and MRONJ staging, EC was predominant in stage 3 and DS in stage 2. IAN and PF demonstrated greater association with stage 3. In conclusion, the higher the clinical staging, the greater the severity of the bone alteration. Panoramic radiographic examination is a useful screening tool in patients submitted to antiresorptive therapy. |
| format | Article |
| id | doaj-art-4bbff4a566d448a994af79204219b430 |
| institution | Kabale University |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-4bbff4a566d448a994af79204219b4302025-02-03T01:25:23ZengWileyInternational Journal of Dentistry1687-87281687-87362017-01-01201710.1155/2017/31903013190301Radiographic Findings in Patients with Medication-Related Osteonecrosis of the JawCamila Lopes Cardoso0Carolina Arrabal Barros1Cláudia Curra2Luciana Maria Paes da Silva Ramos Fernandes3Solange de Oliveira Braga Franzolin4Joel Santiago Ferreira Júnior5Carlos César De Antoni6Marcos Martins Curi7Department of Oral Surgery, Universidade do Sagrado Coração, Bauru, SP, BrazilDepartment of Oral Surgery, Universidade do Sagrado Coração, Bauru, SP, BrazilDepartment of Oral Surgery, Universidade do Sagrado Coração, Bauru, SP, BrazilDepartment of Oral Radiology, Universidade de São Paulo, São Paulo, SP, BrazilDepartment of Biostatistics, Universidade do Sagrado Coração, Bauru, SP, BrazilDepartment of Biostatistics, Universidade do Sagrado Coração, Bauru, SP, BrazilDepartment of Oral Surgery, Universidade do Sagrado Coração, Bauru, SP, BrazilDepartment of Stomatology, Hospital Santa Catarina, São Paulo, SP, BrazilA retrospective study was conducted of the records and panoramic radiographs of 35 patients treated with bisphosphonates (BP) and diagnosed with MRONJ. Panoramic radiography was used for evaluation, by two examiners, the following findings were subject of search: osteolysis (OT), cortical bone erosion (EC), bone sclerosis focal (FS) and diffuse (DS), bone sequestration (BS), thickening of lamina dura (TD), prominence of the inferior alveolar nerve canal (IAN), persisting alveolar sockets (SK), and the presence of a pathological fracture (PF). Medical information and staging were also recorded in order to correlate with radiographic findings. Bone sclerosis was the most frequent alteration, followed by OT and TD. The mandible was more affected than the maxilla. There was no significant difference between genders or significant correlation between the number of injuries with age and duration of BP usage. Considering the association between the radiographic findings and MRONJ staging, EC was predominant in stage 3 and DS in stage 2. IAN and PF demonstrated greater association with stage 3. In conclusion, the higher the clinical staging, the greater the severity of the bone alteration. Panoramic radiographic examination is a useful screening tool in patients submitted to antiresorptive therapy.http://dx.doi.org/10.1155/2017/3190301 |
| spellingShingle | Camila Lopes Cardoso Carolina Arrabal Barros Cláudia Curra Luciana Maria Paes da Silva Ramos Fernandes Solange de Oliveira Braga Franzolin Joel Santiago Ferreira Júnior Carlos César De Antoni Marcos Martins Curi Radiographic Findings in Patients with Medication-Related Osteonecrosis of the Jaw International Journal of Dentistry |
| title | Radiographic Findings in Patients with Medication-Related Osteonecrosis of the Jaw |
| title_full | Radiographic Findings in Patients with Medication-Related Osteonecrosis of the Jaw |
| title_fullStr | Radiographic Findings in Patients with Medication-Related Osteonecrosis of the Jaw |
| title_full_unstemmed | Radiographic Findings in Patients with Medication-Related Osteonecrosis of the Jaw |
| title_short | Radiographic Findings in Patients with Medication-Related Osteonecrosis of the Jaw |
| title_sort | radiographic findings in patients with medication related osteonecrosis of the jaw |
| url | http://dx.doi.org/10.1155/2017/3190301 |
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