Relapsing Polychondritis in a Patient with Ankylosing Spondylitis Using Etanercept
Relapsing polychondritis (RP) is an autoimmune disease characterized by recurrent episodes of inflammation and progressive destruction of cartilaginous tissues, especially of the ears, nose, joints, and tracheobronchial tree. Its etiology is not well understood, but some studies have linked its path...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2014/353782 |
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| author | Valderilio Feijó Azevedo Natalia Bassalobre Galli Alais Daiane Fadini Kleinfelder Julia Farabolini D’Ippolito Andressa Gulin Tolentino Eduardo Paiva |
| author_facet | Valderilio Feijó Azevedo Natalia Bassalobre Galli Alais Daiane Fadini Kleinfelder Julia Farabolini D’Ippolito Andressa Gulin Tolentino Eduardo Paiva |
| author_sort | Valderilio Feijó Azevedo |
| collection | DOAJ |
| description | Relapsing polychondritis (RP) is an autoimmune disease characterized by recurrent episodes of inflammation and progressive destruction of cartilaginous tissues, especially of the ears, nose, joints, and tracheobronchial tree. Its etiology is not well understood, but some studies have linked its pathophysiology with autoimmune disease and autoantibody production. We described a case of a 46-year-old male patient with ankylosing spondylitis who developed RP after the use of etanercept. Few similar cases have been described in the literature. However, they show a possible association between the use of biological inhibitors of tumor necrosis factor (anti-TNFα), which potentially produces autoantibodies, and the development of RP. The treatment was based on data in the literature and included the cessation of biological therapy and the addition of corticosteroids with substantial improvement. |
| format | Article |
| id | doaj-art-4bb4a95125ba40f8813d12f6ce59405e |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-4bb4a95125ba40f8813d12f6ce59405e2025-02-03T01:24:31ZengWileyCase Reports in Rheumatology2090-68892090-68972014-01-01201410.1155/2014/353782353782Relapsing Polychondritis in a Patient with Ankylosing Spondylitis Using EtanerceptValderilio Feijó Azevedo0Natalia Bassalobre Galli1Alais Daiane Fadini Kleinfelder2Julia Farabolini D’Ippolito3Andressa Gulin Tolentino4Eduardo Paiva5Division of Rheumatology, Department of Clinical Medicine, Federal University of Paraná, 80060-900 Curitiba, PR, BrazilFederal University of Paraná, 80060-900 Curitiba, PR, BrazilFederal University of Paraná, 80060-900 Curitiba, PR, BrazilFederal University of Paraná, 80060-900 Curitiba, PR, BrazilFederal University of Paraná, 80060-900 Curitiba, PR, BrazilDivision of Rheumatology, Department of Clinical Medicine, Federal University of Paraná, 80060-900 Curitiba, PR, BrazilRelapsing polychondritis (RP) is an autoimmune disease characterized by recurrent episodes of inflammation and progressive destruction of cartilaginous tissues, especially of the ears, nose, joints, and tracheobronchial tree. Its etiology is not well understood, but some studies have linked its pathophysiology with autoimmune disease and autoantibody production. We described a case of a 46-year-old male patient with ankylosing spondylitis who developed RP after the use of etanercept. Few similar cases have been described in the literature. However, they show a possible association between the use of biological inhibitors of tumor necrosis factor (anti-TNFα), which potentially produces autoantibodies, and the development of RP. The treatment was based on data in the literature and included the cessation of biological therapy and the addition of corticosteroids with substantial improvement.http://dx.doi.org/10.1155/2014/353782 |
| spellingShingle | Valderilio Feijó Azevedo Natalia Bassalobre Galli Alais Daiane Fadini Kleinfelder Julia Farabolini D’Ippolito Andressa Gulin Tolentino Eduardo Paiva Relapsing Polychondritis in a Patient with Ankylosing Spondylitis Using Etanercept Case Reports in Rheumatology |
| title | Relapsing Polychondritis in a Patient with Ankylosing Spondylitis Using Etanercept |
| title_full | Relapsing Polychondritis in a Patient with Ankylosing Spondylitis Using Etanercept |
| title_fullStr | Relapsing Polychondritis in a Patient with Ankylosing Spondylitis Using Etanercept |
| title_full_unstemmed | Relapsing Polychondritis in a Patient with Ankylosing Spondylitis Using Etanercept |
| title_short | Relapsing Polychondritis in a Patient with Ankylosing Spondylitis Using Etanercept |
| title_sort | relapsing polychondritis in a patient with ankylosing spondylitis using etanercept |
| url | http://dx.doi.org/10.1155/2014/353782 |
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