Risk Factors for Neonatal Sepsis in Pregnant Women with Premature Rupture of the Membrane
Background. Premature rupture of the membrane (PROM) is associated with high maternal as well as perinatal morbidity and mortality risks. It occurs in 5 to 10% of all pregnancy while incidence of amniotic membrane infection varies from 6 to 10%. This study aimed to determine the incidence of neonata...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Pregnancy |
| Online Access: | http://dx.doi.org/10.1155/2018/4823404 |
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| author | Dwiana Ocviyanti William Timotius Wahono |
| author_facet | Dwiana Ocviyanti William Timotius Wahono |
| author_sort | Dwiana Ocviyanti |
| collection | DOAJ |
| description | Background. Premature rupture of the membrane (PROM) is associated with high maternal as well as perinatal morbidity and mortality risks. It occurs in 5 to 10% of all pregnancy while incidence of amniotic membrane infection varies from 6 to 10%. This study aimed to determine the incidence of neonatal sepsis in Cipto Mangunkusumo Hospital and the risk factors. Methods. A cross-sectional study was done in Cipto Mangunkusumo Hospital, Jakarta, from December 2016 to June 2017. The study used total sampling method including all pregnant women with gestational age of 20 weeks or more experiencing PROM, who came to the hospital at that time. Samples with existing comorbidities such as diabetes mellitus or other serious systemic illnesses such as heart disease or autoimmune condition were excluded from the analysis. Results. A total of 405 pregnant women with PROM were included in this study. There were 21 cases (5.2%) of neonatal sepsis. The analysis showed that risk of neonatal sepsis was higher in pregnant women with prolonged rupture of membrane for ≥ 18 hours before hospital admission (OR 3.08), prolonged rupture of membrane for ≥ 15 hours during hospitalization (OR 7.32), and prolonged rupture of membrane for ≥ 48 hours until birth (OR 5.77). The risk of neonatal sepsis was higher in preterm pregnancy with gestational age of <37 weeks (OR 18.59). Conclusion. Risk of neonatal sepsis is higher in longer duration of prolonged rupture of membrane as well as preterm pregnancy. |
| format | Article |
| id | doaj-art-4b9e14822d5748de8369829c518275e4 |
| institution | Kabale University |
| issn | 2090-2727 2090-2735 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Pregnancy |
| spelling | doaj-art-4b9e14822d5748de8369829c518275e42025-02-03T05:51:38ZengWileyJournal of Pregnancy2090-27272090-27352018-01-01201810.1155/2018/48234044823404Risk Factors for Neonatal Sepsis in Pregnant Women with Premature Rupture of the MembraneDwiana Ocviyanti0William Timotius Wahono1Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDepartment of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, IndonesiaBackground. Premature rupture of the membrane (PROM) is associated with high maternal as well as perinatal morbidity and mortality risks. It occurs in 5 to 10% of all pregnancy while incidence of amniotic membrane infection varies from 6 to 10%. This study aimed to determine the incidence of neonatal sepsis in Cipto Mangunkusumo Hospital and the risk factors. Methods. A cross-sectional study was done in Cipto Mangunkusumo Hospital, Jakarta, from December 2016 to June 2017. The study used total sampling method including all pregnant women with gestational age of 20 weeks or more experiencing PROM, who came to the hospital at that time. Samples with existing comorbidities such as diabetes mellitus or other serious systemic illnesses such as heart disease or autoimmune condition were excluded from the analysis. Results. A total of 405 pregnant women with PROM were included in this study. There were 21 cases (5.2%) of neonatal sepsis. The analysis showed that risk of neonatal sepsis was higher in pregnant women with prolonged rupture of membrane for ≥ 18 hours before hospital admission (OR 3.08), prolonged rupture of membrane for ≥ 15 hours during hospitalization (OR 7.32), and prolonged rupture of membrane for ≥ 48 hours until birth (OR 5.77). The risk of neonatal sepsis was higher in preterm pregnancy with gestational age of <37 weeks (OR 18.59). Conclusion. Risk of neonatal sepsis is higher in longer duration of prolonged rupture of membrane as well as preterm pregnancy.http://dx.doi.org/10.1155/2018/4823404 |
| spellingShingle | Dwiana Ocviyanti William Timotius Wahono Risk Factors for Neonatal Sepsis in Pregnant Women with Premature Rupture of the Membrane Journal of Pregnancy |
| title | Risk Factors for Neonatal Sepsis in Pregnant Women with Premature Rupture of the Membrane |
| title_full | Risk Factors for Neonatal Sepsis in Pregnant Women with Premature Rupture of the Membrane |
| title_fullStr | Risk Factors for Neonatal Sepsis in Pregnant Women with Premature Rupture of the Membrane |
| title_full_unstemmed | Risk Factors for Neonatal Sepsis in Pregnant Women with Premature Rupture of the Membrane |
| title_short | Risk Factors for Neonatal Sepsis in Pregnant Women with Premature Rupture of the Membrane |
| title_sort | risk factors for neonatal sepsis in pregnant women with premature rupture of the membrane |
| url | http://dx.doi.org/10.1155/2018/4823404 |
| work_keys_str_mv | AT dwianaocviyanti riskfactorsforneonatalsepsisinpregnantwomenwithprematureruptureofthemembrane AT williamtimotiuswahono riskfactorsforneonatalsepsisinpregnantwomenwithprematureruptureofthemembrane |