Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities
In this study, we used the aqueous extract of garlic tunicate leaf to reduce a mixture of equal amounts of ruthenium chloride, silver nitrate, and palladium acetate for the biosynthesis of ruthenium/silver/palladium trimetallic nanocomposite (Ru/Ag/Pd)-Np. Some physicochemical tools were used for na...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2022/4593086 |
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| author | Shaimaa Hussein Ayman M. Mahmoud Hassan A. Elgebaly Omnia Magdy Hendawy Emad H. M. Hassanein Shaima M. N. Moustafa Nasser F. Alotaibi Amr M. Nassar |
| author_facet | Shaimaa Hussein Ayman M. Mahmoud Hassan A. Elgebaly Omnia Magdy Hendawy Emad H. M. Hassanein Shaima M. N. Moustafa Nasser F. Alotaibi Amr M. Nassar |
| author_sort | Shaimaa Hussein |
| collection | DOAJ |
| description | In this study, we used the aqueous extract of garlic tunicate leaf to reduce a mixture of equal amounts of ruthenium chloride, silver nitrate, and palladium acetate for the biosynthesis of ruthenium/silver/palladium trimetallic nanocomposite (Ru/Ag/Pd)-Np. Some physicochemical tools were used for nanocomposite characterization, including Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermal gravimetric analysis (TGA), UV-Vis spectroscopy (UV-Vis), scanning electron microscope (SEM), and transmittance electron microscope (TEM). XRD revealed that the crystal size of the nanocomposite is 15.67 nm. The TEM images showed that the particle size ranged 50–90 nm. The antimicrobial efficacy of the nanocomposite was examined against Aspergillus flavus, Aspergillus niger, Candida albicans, Candida glabrata, Escherichia coli, and Bacillus cereus. The results showed a potent antimicrobial activity toward all tested microorganisms. (Ru/Ag/Pd)-Np showed antiproliferative activity against Caco-2, HepG2, and K562 cell lines. The antiproliferative potential of (Ru/Ag/Pd)-Np was significantly improved following UV irradiation. |
| format | Article |
| id | doaj-art-4b971899e6dc4965bbd8ae6d1242444e |
| institution | Kabale University |
| issn | 2090-9071 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-4b971899e6dc4965bbd8ae6d1242444e2025-02-03T05:49:20ZengWileyJournal of Chemistry2090-90712022-01-01202210.1155/2022/4593086Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer ActivitiesShaimaa Hussein0Ayman M. Mahmoud1Hassan A. Elgebaly2Omnia Magdy Hendawy3Emad H. M. Hassanein4Shaima M. N. Moustafa5Nasser F. Alotaibi6Amr M. Nassar7Department of PharmacologyPhysiology DivisionDepartment of BiologyDepartment of PharmacologyDepartment of Pharmacology and ToxicologyBiology.Department College of ScienceChemistry DepartmentChemistry DepartmentIn this study, we used the aqueous extract of garlic tunicate leaf to reduce a mixture of equal amounts of ruthenium chloride, silver nitrate, and palladium acetate for the biosynthesis of ruthenium/silver/palladium trimetallic nanocomposite (Ru/Ag/Pd)-Np. Some physicochemical tools were used for nanocomposite characterization, including Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermal gravimetric analysis (TGA), UV-Vis spectroscopy (UV-Vis), scanning electron microscope (SEM), and transmittance electron microscope (TEM). XRD revealed that the crystal size of the nanocomposite is 15.67 nm. The TEM images showed that the particle size ranged 50–90 nm. The antimicrobial efficacy of the nanocomposite was examined against Aspergillus flavus, Aspergillus niger, Candida albicans, Candida glabrata, Escherichia coli, and Bacillus cereus. The results showed a potent antimicrobial activity toward all tested microorganisms. (Ru/Ag/Pd)-Np showed antiproliferative activity against Caco-2, HepG2, and K562 cell lines. The antiproliferative potential of (Ru/Ag/Pd)-Np was significantly improved following UV irradiation.http://dx.doi.org/10.1155/2022/4593086 |
| spellingShingle | Shaimaa Hussein Ayman M. Mahmoud Hassan A. Elgebaly Omnia Magdy Hendawy Emad H. M. Hassanein Shaima M. N. Moustafa Nasser F. Alotaibi Amr M. Nassar Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities Journal of Chemistry |
| title | Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities |
| title_full | Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities |
| title_fullStr | Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities |
| title_full_unstemmed | Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities |
| title_short | Green Synthesis of Trimetallic Nanocomposite (Ru/Ag/Pd)-Np and Its In Vitro Antimicrobial and Anticancer Activities |
| title_sort | green synthesis of trimetallic nanocomposite ru ag pd np and its in vitro antimicrobial and anticancer activities |
| url | http://dx.doi.org/10.1155/2022/4593086 |
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