Coinfection of malaria and scrub typhus in a toddler: First report from South India
Tropical infections are common in South Asia, including India. However, coinfections among the different diseases are rare in children. We report a case of malaria-scrub typhus coinfection in a toddler from South India. A 3-year-old boy presented with fever. He was pale, dull-looking and had hepatos...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Journal of Current Research in Scientific Medicine |
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| Online Access: | https://journals.lww.com/10.4103/jcrsm.jcrsm_125_23 |
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| author | Nandini Vasudevan Sawantharia Jaganathan Priya Jose Peter Prasanth Kumar Kommu |
| author_facet | Nandini Vasudevan Sawantharia Jaganathan Priya Jose Peter Prasanth Kumar Kommu |
| author_sort | Nandini Vasudevan |
| collection | DOAJ |
| description | Tropical infections are common in South Asia, including India. However, coinfections among the different diseases are rare in children. We report a case of malaria-scrub typhus coinfection in a toddler from South India. A 3-year-old boy presented with fever. He was pale, dull-looking and had hepatosplenomegaly.. There was mild leukocytosis with positive C reactive protein. Rapid malarial antigen was positive, and started on antimalarial therapy. Fever was persisting after 48 h and doxycycline was started. Scrub typhus immunoglobulin M was positive. He responded dramatically to doxycycline, and in 24 hours, he became afebrile. The prevalence of this coinfection was studied by Wilairatana et al. in 2021 and showed a low prevalence of 0%–1%. Our case is unique and rare as this has not been reported in a toddler. Children with acute undifferentiated fever which is not responding to therapy within 48 hours must be investigated for concurrent infection. |
| format | Article |
| id | doaj-art-4b9350f0904047cd907cb764803b7660 |
| institution | Kabale University |
| issn | 2542-6273 2455-3069 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Current Research in Scientific Medicine |
| spelling | doaj-art-4b9350f0904047cd907cb764803b76602025-01-23T05:27:35ZengWolters Kluwer Medknow PublicationsJournal of Current Research in Scientific Medicine2542-62732455-30692024-01-0110113413610.4103/jcrsm.jcrsm_125_23Coinfection of malaria and scrub typhus in a toddler: First report from South IndiaNandini VasudevanSawantharia JaganathanPriya JosePeter Prasanth Kumar KommuTropical infections are common in South Asia, including India. However, coinfections among the different diseases are rare in children. We report a case of malaria-scrub typhus coinfection in a toddler from South India. A 3-year-old boy presented with fever. He was pale, dull-looking and had hepatosplenomegaly.. There was mild leukocytosis with positive C reactive protein. Rapid malarial antigen was positive, and started on antimalarial therapy. Fever was persisting after 48 h and doxycycline was started. Scrub typhus immunoglobulin M was positive. He responded dramatically to doxycycline, and in 24 hours, he became afebrile. The prevalence of this coinfection was studied by Wilairatana et al. in 2021 and showed a low prevalence of 0%–1%. Our case is unique and rare as this has not been reported in a toddler. Children with acute undifferentiated fever which is not responding to therapy within 48 hours must be investigated for concurrent infection.https://journals.lww.com/10.4103/jcrsm.jcrsm_125_23coinfectionmalariascrub typhustoddler |
| spellingShingle | Nandini Vasudevan Sawantharia Jaganathan Priya Jose Peter Prasanth Kumar Kommu Coinfection of malaria and scrub typhus in a toddler: First report from South India Journal of Current Research in Scientific Medicine coinfection malaria scrub typhus toddler |
| title | Coinfection of malaria and scrub typhus in a toddler: First report from South India |
| title_full | Coinfection of malaria and scrub typhus in a toddler: First report from South India |
| title_fullStr | Coinfection of malaria and scrub typhus in a toddler: First report from South India |
| title_full_unstemmed | Coinfection of malaria and scrub typhus in a toddler: First report from South India |
| title_short | Coinfection of malaria and scrub typhus in a toddler: First report from South India |
| title_sort | coinfection of malaria and scrub typhus in a toddler first report from south india |
| topic | coinfection malaria scrub typhus toddler |
| url | https://journals.lww.com/10.4103/jcrsm.jcrsm_125_23 |
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