Developing and validating a prognostic disulfidptosis-related signature for glioblastoma: predicting radioresistance and synergestic effect with immunotherapy

Developing and validating a prognostic disulfidptosis-related signature for glioblastoma: predicting radioresistance and synergestic effect with immunotherapy

Abstract Background Programmed cell death (PCD) modulated radioresistance is one of the predominant causes of treatment failure in glioblastoma (GBM). Disulfidptosis, a newly discovered form of PCD, plays a crucial role in GBM progression. However, the association among disulfidptosis, radiosensitiv...

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Bibliographic Details
Main Authors: Chen Chen, Peixin Tan, Wenqing Feng, Yuan Lei, Shushu Hu, Dehuan Xie, Yantan Liu, Chen Ren, Shasha Du
Format: Article
Language:English
Published: Springer 2025-03-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Disulfidptosis
Tumor microenvironment
Glioblastoma
Radiotherapy
Immunotherapy
Online Access:https://doi.org/10.1007/s00432-025-06159-0
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