Biocorrosion studies of novel Zr-Co-Ti based thin-film metallic glass alloys in simulated body fluids and in-vitro cytotoxicity analysis

Abstract A novel Zr-Co-Ti-based thin film metallic glass (TFMG) compositions (Zr60Co30Ti10, Zr55Co35Ti10, Zr50Co40Ti10) were synthesized via melt-spinning. These alloys demonstrate excellent anti-corrosion properties in Simulated Body Fluid (SBF) solutions, including Artificial Saliva Solution (ASS)...

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Main Authors: Shubhra Shitole, S. Vincent, Abdel-Hamid Ismail Mourad, Jisha Pillai, Mainak Dutta, Dali Vilma Francis
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Journal of King Saud University: Engineering Sciences
Subjects:
Online Access:https://doi.org/10.1007/s44444-025-00028-4
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Summary:Abstract A novel Zr-Co-Ti-based thin film metallic glass (TFMG) compositions (Zr60Co30Ti10, Zr55Co35Ti10, Zr50Co40Ti10) were synthesized via melt-spinning. These alloys demonstrate excellent anti-corrosion properties in Simulated Body Fluid (SBF) solutions, including Artificial Saliva Solution (ASS), Phosphate Buffered Solution (PBS), Artificial Blood Plasma Solution (ABP), and Hank’s Balanced Saline Solution (HBSS). Potentiodynamic polarization (PDP) and electrochemical impedance spectroscopy (EIS) revealed exceptional corrosion resistance of the compositions, with a passive current density in the order of 10⁻11. SEM and EDS analysis examined the corroded surfaces of the TFMG samples. Cytocompatibility of the TFMG alloys was assessed using L-929 mice fibroblast cell lines, and the compositions showcased good antibacterial and biofilm properties against Listeria monocytogenes and Escherichia coli. Zr and Co content influenced the alloys' anticorrosion and cytocompatibility, supporting their potential as biomedical implants.
ISSN:1018-3639
2213-1558