1,5-Acrylodan: A Fluorescent Bioconjugate Sensor of Protic Environments
1,5-Acrylodan (1-(5-(dimethylamino)naphthalen-1-yl)prop-2-en-1-one) is prepared in six steps from 1-nitronaphthalene and 19% overall yield. The last three steps involve an aryllithium-directed nucleophilic addition, catalytic Kulinkovich cyclopropanation, and copper-catalyzed oxidative ring-opening...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-11-01
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| Series: | Organics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-401X/5/4/26 |
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