Surgery in a Patient with Haemophilia A and Lymphoma

An increased incidence of haematologic malignancies and other cancer types among patients with haemophilia compared with matched controls has been reported in several longitudinal studies. Tumours initially misdiagnosed as haematomas and conversely haematomas mistaken for tumours have been reported....

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Main Authors: M. S. Cruz, J. Santillan, J. Lesser, J. Ortiz, L. Forzani, P. Plaza
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2020/4852428
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author M. S. Cruz
J. Santillan
J. Lesser
J. Ortiz
L. Forzani
P. Plaza
author_facet M. S. Cruz
J. Santillan
J. Lesser
J. Ortiz
L. Forzani
P. Plaza
author_sort M. S. Cruz
collection DOAJ
description An increased incidence of haematologic malignancies and other cancer types among patients with haemophilia compared with matched controls has been reported in several longitudinal studies. Tumours initially misdiagnosed as haematomas and conversely haematomas mistaken for tumours have been reported. Here, we describe the case of a 43-year-old man with severe haemophilia A and a diffuse large B-cell lymphoma, originally diagnosed as a haematoma, who underwent a splenectomy and several associated surgeries as part of his lymphoma treatment. Perioperative treatment with octanate® (human coagulation factor VIII) enabled the successful performance of all surgical interventions required in the context of lymphoma treatment. Nevertheless, differential diagnosis of posttraumatic haematoma in patients with haemophilia should include the consideration of malignancy.
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institution Kabale University
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publishDate 2020-01-01
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series Case Reports in Hematology
spelling doaj-art-4b3b9dc90176493081ec17875089a13e2025-02-03T06:06:43ZengWileyCase Reports in Hematology2090-65602090-65792020-01-01202010.1155/2020/48524284852428Surgery in a Patient with Haemophilia A and LymphomaM. S. Cruz0J. Santillan1J. Lesser2J. Ortiz3L. Forzani4P. Plaza5Fundación de la Hemofilia de Salta, Salta, ArgentinaFundación de la Hemofilia de Salta, Salta, ArgentinaFundación de la Hemofilia de Salta, Salta, ArgentinaFundación de la Hemofilia de Salta, Salta, ArgentinaFundación de la Hemofilia de Salta, Salta, ArgentinaFundación de la Hemofilia de Salta, Salta, ArgentinaAn increased incidence of haematologic malignancies and other cancer types among patients with haemophilia compared with matched controls has been reported in several longitudinal studies. Tumours initially misdiagnosed as haematomas and conversely haematomas mistaken for tumours have been reported. Here, we describe the case of a 43-year-old man with severe haemophilia A and a diffuse large B-cell lymphoma, originally diagnosed as a haematoma, who underwent a splenectomy and several associated surgeries as part of his lymphoma treatment. Perioperative treatment with octanate® (human coagulation factor VIII) enabled the successful performance of all surgical interventions required in the context of lymphoma treatment. Nevertheless, differential diagnosis of posttraumatic haematoma in patients with haemophilia should include the consideration of malignancy.http://dx.doi.org/10.1155/2020/4852428
spellingShingle M. S. Cruz
J. Santillan
J. Lesser
J. Ortiz
L. Forzani
P. Plaza
Surgery in a Patient with Haemophilia A and Lymphoma
Case Reports in Hematology
title Surgery in a Patient with Haemophilia A and Lymphoma
title_full Surgery in a Patient with Haemophilia A and Lymphoma
title_fullStr Surgery in a Patient with Haemophilia A and Lymphoma
title_full_unstemmed Surgery in a Patient with Haemophilia A and Lymphoma
title_short Surgery in a Patient with Haemophilia A and Lymphoma
title_sort surgery in a patient with haemophilia a and lymphoma
url http://dx.doi.org/10.1155/2020/4852428
work_keys_str_mv AT mscruz surgeryinapatientwithhaemophiliaaandlymphoma
AT jsantillan surgeryinapatientwithhaemophiliaaandlymphoma
AT jlesser surgeryinapatientwithhaemophiliaaandlymphoma
AT jortiz surgeryinapatientwithhaemophiliaaandlymphoma
AT lforzani surgeryinapatientwithhaemophiliaaandlymphoma
AT pplaza surgeryinapatientwithhaemophiliaaandlymphoma