Modeling of pharmacokinetic/pharmacodynamic parameters in regular intermittent intravenous infusion and translational application of the models in personalized antibiotics dosing
Abstract Objective Quantitative calculation models for the ratio of daily area under the concentration–time curve (AUC24) to the minimum inhibitory concentration (MIC) (i.e., AUC24/MIC) and the amount of time that concentration stays above the MIC during a dosing interval (i.e., T>MIC%) in regula...
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| Main Author: | Xiangqing Song |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
|
| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-025-06832-5 |
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