More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19

Background. Although severe pneumonia and respiratory compromise have remained the predominant complications of coronavirus disease 19, we are now learning this virus is much more varied in its presentation. In particular, there are increasingly reported cases of thromboembolic events occurring in i...

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Main Authors: Jahinover Mazo, Sukhdev Singh, Zohaib Khan, Allison Foster, Ecaterina Komarnitsky, Abhiram Nagaraj, Soham Patel, Vinaya Kikkeri
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2020/4812036
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author Jahinover Mazo
Sukhdev Singh
Zohaib Khan
Allison Foster
Ecaterina Komarnitsky
Abhiram Nagaraj
Soham Patel
Vinaya Kikkeri
author_facet Jahinover Mazo
Sukhdev Singh
Zohaib Khan
Allison Foster
Ecaterina Komarnitsky
Abhiram Nagaraj
Soham Patel
Vinaya Kikkeri
author_sort Jahinover Mazo
collection DOAJ
description Background. Although severe pneumonia and respiratory compromise have remained the predominant complications of coronavirus disease 19, we are now learning this virus is much more varied in its presentation. In particular, there are increasingly reported cases of thromboembolic events occurring in infected patients. Case Report. In this report, we present two patients, both under the age of 40 with known risk factors for venous thromboembolism, who presented with respiratory distress. Both patients were diagnosed with SARS-CoV-2 pneumonia and pulmonary embolism requiring management with anticoagulation. Both patients were discharged after a short course in the hospital. Conclusion. The discussion of a hypercoagulable state induced by coronavirus disease 19 has been well documented; however, the exact mechanisms remain unknown. We suspect that a prothrombotic inflammatory response provoked by coronavirus disease could be the culprit, acting as an additive effect on middle-aged patients with known risk factors for venous thromboembolism. We recommend clinicians closely monitor those with known risk factors for pulmonary embolism.
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institution Kabale University
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publishDate 2020-01-01
publisher Wiley
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series Case Reports in Medicine
spelling doaj-art-4b336b510a6846968a4938c6a67265f02025-02-03T05:53:54ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/48120364812036More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19Jahinover Mazo0Sukhdev Singh1Zohaib Khan2Allison Foster3Ecaterina Komarnitsky4Abhiram Nagaraj5Soham Patel6Vinaya Kikkeri7Department of Radiology, Richmond University Medical Center, New York, NY, USACollege of Medicine, American University of Antigua, New York, NY, USACollege of Medicine, American University of Antigua, New York, NY, USACollege of Medicine, American University of Antigua, New York, NY, USACollege of Medicine, American University of Antigua, New York, NY, USADepartment of Radiology, Richmond University Medical Center, New York, NY, USADepartment of Radiology, Richmond University Medical Center, New York, NY, USADepartment of Radiology, Richmond University Medical Center, New York, NY, USABackground. Although severe pneumonia and respiratory compromise have remained the predominant complications of coronavirus disease 19, we are now learning this virus is much more varied in its presentation. In particular, there are increasingly reported cases of thromboembolic events occurring in infected patients. Case Report. In this report, we present two patients, both under the age of 40 with known risk factors for venous thromboembolism, who presented with respiratory distress. Both patients were diagnosed with SARS-CoV-2 pneumonia and pulmonary embolism requiring management with anticoagulation. Both patients were discharged after a short course in the hospital. Conclusion. The discussion of a hypercoagulable state induced by coronavirus disease 19 has been well documented; however, the exact mechanisms remain unknown. We suspect that a prothrombotic inflammatory response provoked by coronavirus disease could be the culprit, acting as an additive effect on middle-aged patients with known risk factors for venous thromboembolism. We recommend clinicians closely monitor those with known risk factors for pulmonary embolism.http://dx.doi.org/10.1155/2020/4812036
spellingShingle Jahinover Mazo
Sukhdev Singh
Zohaib Khan
Allison Foster
Ecaterina Komarnitsky
Abhiram Nagaraj
Soham Patel
Vinaya Kikkeri
More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
Case Reports in Medicine
title More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
title_full More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
title_fullStr More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
title_full_unstemmed More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
title_short More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
title_sort more than just pneumonia acute pulmonary embolism in two middle aged patients with covid 19
url http://dx.doi.org/10.1155/2020/4812036
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