Acute Cytotoxic Cerebellar Edema Subsequent to Fentanyl Patch Intoxication in an Infant

The opioid epidemic continues to have devastating consequences for children and families across the United States with rising prevalence of opioid use and abuse. Given the ease of access to these medications, accidental ingestion and overdose by children are becoming increasingly more common. The re...

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Main Authors: Lindsey N. Haut, Rupa Radhakrishnan, Riad Lutfi, Louise W. Kao, Laurie L. Ackerman
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2021/9449565
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author Lindsey N. Haut
Rupa Radhakrishnan
Riad Lutfi
Louise W. Kao
Laurie L. Ackerman
author_facet Lindsey N. Haut
Rupa Radhakrishnan
Riad Lutfi
Louise W. Kao
Laurie L. Ackerman
author_sort Lindsey N. Haut
collection DOAJ
description The opioid epidemic continues to have devastating consequences for children and families across the United States with rising prevalence of opioid use and abuse. Given the ease of access to these medications, accidental ingestion and overdose by children are becoming increasingly more common. The recognition of opioid-induced neurotoxicity and the associated life-threatening complication of acute cerebellar cytotoxic edema are crucial, as are the high morbidity and mortality without timely intervention. We discuss an infant with acute cytotoxic cerebellar edema following mucosal exposure to a transdermal fentanyl patch.
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institution Kabale University
issn 2090-6420
2090-6439
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Case Reports in Critical Care
spelling doaj-art-4b313bd38d7a42acb654618adc21f5982025-02-03T01:26:59ZengWileyCase Reports in Critical Care2090-64202090-64392021-01-01202110.1155/2021/94495659449565Acute Cytotoxic Cerebellar Edema Subsequent to Fentanyl Patch Intoxication in an InfantLindsey N. Haut0Rupa Radhakrishnan1Riad Lutfi2Louise W. Kao3Laurie L. Ackerman4Division of Pediatric Emergency Medicine, Department of Emergency Medicine, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN, USADepartment of Radiology, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN, USADivision of Pediatric Critical Care Medicine, Department of Pediatrics, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN, USADepartment of Toxicology, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN, USADepartment of Neurosurgery, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN, USAThe opioid epidemic continues to have devastating consequences for children and families across the United States with rising prevalence of opioid use and abuse. Given the ease of access to these medications, accidental ingestion and overdose by children are becoming increasingly more common. The recognition of opioid-induced neurotoxicity and the associated life-threatening complication of acute cerebellar cytotoxic edema are crucial, as are the high morbidity and mortality without timely intervention. We discuss an infant with acute cytotoxic cerebellar edema following mucosal exposure to a transdermal fentanyl patch.http://dx.doi.org/10.1155/2021/9449565
spellingShingle Lindsey N. Haut
Rupa Radhakrishnan
Riad Lutfi
Louise W. Kao
Laurie L. Ackerman
Acute Cytotoxic Cerebellar Edema Subsequent to Fentanyl Patch Intoxication in an Infant
Case Reports in Critical Care
title Acute Cytotoxic Cerebellar Edema Subsequent to Fentanyl Patch Intoxication in an Infant
title_full Acute Cytotoxic Cerebellar Edema Subsequent to Fentanyl Patch Intoxication in an Infant
title_fullStr Acute Cytotoxic Cerebellar Edema Subsequent to Fentanyl Patch Intoxication in an Infant
title_full_unstemmed Acute Cytotoxic Cerebellar Edema Subsequent to Fentanyl Patch Intoxication in an Infant
title_short Acute Cytotoxic Cerebellar Edema Subsequent to Fentanyl Patch Intoxication in an Infant
title_sort acute cytotoxic cerebellar edema subsequent to fentanyl patch intoxication in an infant
url http://dx.doi.org/10.1155/2021/9449565
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AT riadlutfi acutecytotoxiccerebellaredemasubsequenttofentanylpatchintoxicationinaninfant
AT louisewkao acutecytotoxiccerebellaredemasubsequenttofentanylpatchintoxicationinaninfant
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